Why am I here?

Frank came to the office for an opinion, sent by his (proactive) family physician.

"I really don't know why I'm here, to be honest."

Two years earlier, Frank had a heart attack, survived and received two stents to his circumflex coronary artery. He now took Zocor and his LDL cholesterol was a reasonably favorable 89 mg, total cholesterol 183 mg.

"I walk with my wife every other day. I've been avoiding fish fries. You'll never see me eat fast food."

Frank was correct: If we were going to engage in the conventional approach to coronary disease, Frank was on the right track. We would have postponed his next heart attack or procedure by a couple of years. Stroke, aneurysm, and other atherosclerotic manifestations would be set back, likewise, a few years.

Would Frank have profound control over his disease? Absolutely not. In fact, his disease had probably advanced a huge amount just in the two years since his stents were placed and he was on his "prevention" program. Without his current effort, his coronary plaque would be expected to grow 30% per year. On Zocor and his modest lifestyle efforts, plaque growth was probably in the 14-28% per year range.

So I explained the unique Track Your Plaque approach to Frank. First, we start with a CT heart scan to establish where he was starting. Although he had two stents in his circumflex artery, we still had two other arteries (LAD, right coronary) to score and track.

We then attempt to identify all hidden causes of his heart disease and then correct them.

Of course, Frank had multiple hidden causes:

--HDL too low at 38 mg/dl
--Small LDL-severe, in fact, with 95% of all LDL particles in the small category
--Triglycerides too high
--Excesses of several triglyceride-containing particles (VLDL, IDL)
--Pre-diabetes--Frank had both a borderline high blood sugar and a high insulin level. This is a sure-fire stimulus to coronary plaque growth.
--A severe deficiency of vitamin D (<20 ng/ml)
--An excessivelyhigh blood pressure during exercise--With a blood pressure of 190/102 on the treadmill.

There were others(!), but that was the bulk of the causes behind Frank's coronary disease.

Once Frank recognized that there was indeed a huge panel of hidden causes for heart disease, not just too much fat in his diet and LDL cholesterol, he jumped into the program head first.

The message: The conventional approach is absurdly oversimplified, a certain path to failure for the majority of people. Even if you don't have known coronary disease like Frank, but just have a heart scan score >zero, the same principles apply to you.
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"I can't do it"

"I can't do it"

Anne sat across from me, bent over and sobbing.

"I can't do it. I just can't do it! I cut out the breads and pasta for two days, then I start dreaming about it!

"And my husband is no help. He knows I'm trying to get off the wheat. But then he brings home a bunch of Danish or something. He knows I can't help myself!"

Having asked hundreds of people to completely remove wheat from their diet, I witness 30% of them go through such emotional and physical turmoil, not uncommonly to the point of tears. For about 10-20% of people who try, it is as hard as quitting cigarettes.

Make no mistake about it: For many people, wheat is addictive. It meets all the criteria for an addictive product: People crave it, consuming it creates a desire for more, lacking it triggers a withdrawal phenomenon. If wheat were illegal, there would surely be an active underground trafficking illicit bagels and pretzels.

Withdrawal consists of fatigue and mental fogginess that usually lasts 5-7 days. Just like quitting smoking, wheat withdrawal is harmless but no less profound in severity.

People who lack an addictive relationship with wheat usually have no idea what I'm talking about. To them, wheat is simply a grain, no different than oats.

But wheat addicts immediately know who they are. They are the ones who can't resist the warm dinner rolls served at the Italian restaurant, need to include something made of wheat at every meal, and crave it every 2 hours (matching the cycle of blood sugar peaks and valleys, the "valley" triggering the craving). When they stop the flow of immediately-released glucose that comes from wheat (with blood sugar peaks that occur higher and faster than table sugar), irresistible cravings kick in. Then watch out: They'll bite your hand off if you reach for that roll before they do.

Break the cycle and the body is confused: Where's the sugar? The body is accustomed to receiving a constant flow of easily-digested sugars.

Once the constant influx of sugars ceases, it takes 5-7 days for metabolism to shift towards fat mobilization as a source of energy. But along with fat mobilization comes a shrinking tummy, reducing the characteristic wheat belly.

If you try to quit smoking, you've got "crutches" like nicotine patches and gum, Zyban, Chantix, hypnosis, and group therapy sessions. If you try and quit wheat, what have you got? Nothing, to my knowledge. Nothing but sheer will power to divorce yourself from this enormously destructive, diabetes-causing, small LDL-increasing, inflammation-provoking, and addictive substance.

Comments (20) -

  • Ghost

    5/30/2009 5:00:26 PM |

    I totally went through that. It took me several tries to quit wheat, and I still mess and have a cookie or a sandwich once every few months-- generally while eating at someone else's house. One thing that helps keep me straight: the ONLY time I get acne anymore is when I eat wheat or chocolate. So now when I think about how much I want a dinner roll, I try to imagine how many spots I will get on my face if I eat it, and ask myself if it's worth it.

    I have read in other sources that wheat, like A1 dairy (from Holstein cows, rather than A2 from Jersey or Guernsey or goats) contains opioid-like molecules, and this is why some people exhibit addictive behaviors in response to them-- and that people who are addicted to wheat also tend to react that way to milk. This certainly matches my own experience.

  • Nancy LC

    5/30/2009 5:15:50 PM |

    When I found out I have a reaction to gluten what I did was repeat to myself "Poison" every time I saw something with wheat (or gluten) in it.  When I smelled it, same thing.  Sometimes I'd use visualizations to imagine it was green and moldering like something poisonous.  It really worked to reprogram me.  I haven't once broken my conditioning and voluntarily ingested gluten, and I don't have the extreme reactions some people do, they can be pretty subtle and take a long time to really make themselves known.

    Maybe it's a technique that other people could find useful.

  • Gretchen

    5/30/2009 6:30:07 PM |

    If it takes a week, maybe you could try some weeklong retreats at which no wheat was available. People would have social support as well as a lack of temptation.

  • Anonymous

    5/30/2009 6:37:44 PM |

    Low Dose Naltrexone might help..

  • thania

    5/30/2009 6:53:33 PM |

    I understand that, I quit smoking 67 days ago, doing low carb, I dont miss as much wheat but rice yes. I have put on 20 lbs low carbing?? I havent ate more that before 1200-1800 cal, depending on the day. But I am a bit depressed dont feel like moving , so less work outs. The heavier I become the less I feel like moving, and I also am having hormonal changes...,
    I feel very unhappy, but dont want to smoke again, this time is for ever.

  • Anne

    5/30/2009 8:21:30 PM |

    I am not the Anne in your post, but I was addicted to wheat. It was my favorite food. I lived on and for breads. Then I discovered I was gluten sensitive and I did go through a withdrawal of about 4 days. After 4 days I noticed my health problems were disappearing. Depression, brain fog and joint pain are 3 of the many symptoms that disappeared. That was 6 yrs ago.  

    Of course giving up gluten does not mean I gave up sugar. I still got my sugar fix with candies and alternative grains. Then I found out my blood sugar was too high so I started eliminating anything that spiked it. I easily lost 20 lbs with low carb eating that got my blood sugar under control.

    Tell Anne that I had dreams about bread in the beginning - they will pass. Now the donuts, breads, cookies and cakes in the stores and at work don't even look good. In fact, I don't like the smell of bread anymore. It takes time, but the cravings do pass.

  • Tom

    5/30/2009 8:49:44 PM |

    I agree, although this leaves open the question of why some people get addicted to things and some people don't (the 10%-20%).

    Meditation and problem-solving seem to be effective cures for all varieties of addiction. Exercise might be used as a substitute for meditation.

  • Lena

    5/30/2009 9:36:50 PM |

    I cut out everything with gluten pretty much immediately once I figured out it made me very ill. That wasn't hard. As for reducing intake of other carbohydrates, I just did that gradually and avoided the desperate cravings. I don't see any particular need to cut down on wheat and refined carbohydrates in one drastic move. Maybe first week, reduce intake by 20%, then another 20% the next week, then in about a month you'll probably be doing fine.

  • Ed

    5/30/2009 10:08:58 PM |

    I've heard "wheat spikes blood sugar more than sucrose" before, and upon reflection, I'm not sure I understand it.

    I assume this is for an equal amount of carbohydrate, ie 100 grams starch (not 100 grams wheat) vs. 100 grams sucrose.

    The problem I see is you're comparing 100 grams of glucose to 50 grams glucose + 50 grams fructose. After looking at it that way, wouldn't you expect your blood *glucose* levels to spike higher with starch than with sugar?

    (Suggesting that sugar is the same as other carbohydrates has become my pet peeve. Technically fructose is a carbohydrate, but the human body processes it totally differently than glucose. It's like saying oleic acid is equivalent to linoleic acid because they're both lipids.)

    Anyway, I have worked grains, sugar and "vegetable" oils out of my diet and my waist just sort of evaporated, while not going hungry -- eating pretty much as much of anything else I want. I would offer moral support for anyone else trying to do the same. Keep at it, the effort is worth the result.

  • Captain Mikee

    5/31/2009 12:06:16 AM |

    Actually, if you are lucky enough to live near a chapter of Food Addicts Anonymous, I think you can get help there. Unfortunately, I do not.

  • Scott W

    5/31/2009 1:45:35 AM |

    I completely agree that wheat is addictive to many and I personally never eat it. However, I'm not sure that your basis for this position, as stated in your posting, passes the credibility test. You have related the addictive capacity of wheat to its starch load, rather than its gluten content.

    If the only reason that wheat is addictive is its starch, then the same position could be taken on potatoes, rice or bananas. But no one ever says they are addicted to boiled potatoes.

    Now, if the patient has a compromised metabolism (type 2 diabetic), then they truly do have a problem with all carbs - not just wheat - and the blood sugar swings that can result.

    However, I think that for a person of normal metabolism (good blood sugar control), it's not the carb content of wheat but its gluten that cause the addiction and other issues.

    Thanks for your ongoing willingness to share your insights from your medical practice.

    Scott W

  • mongander

    5/31/2009 3:25:09 AM |

    In addition to following Dr Davis, I also follow Dr Gabe Mirkin.  So I have compromised and quit wheat, but continue to eat whole intact barley and oats.  Have done well, losing over 60lbs, with the help of exercise.  Haven't had the comprehensive lipid tests nor the heartscan but at age 70, feel good.  Last total cholesterol was 158. Also take niacin, K2, and fish oil.

  • stern

    5/31/2009 4:30:57 PM |

    we need to restrict from carbs since we started with the poisenios wheat ,but we can get along with healthy carbs which is organic whole einkorn sourdough bread ,does any have a tip on how to rise it without yeast please let hear from you

  • Anonymous

    6/3/2009 2:24:54 AM |

    For rising sourdough try Kefir !

  • Shreela

    6/4/2009 12:35:42 PM |

    While waiting for my doctors to diagnose my gut ailment, I thought it sounded like I had a few gluten-intolerance symptoms and was desperate enough to try cutting gluten from my diet to see if I could stop the terrible pain.

    The pain did stop fairly soon after stopping wheat/gluten, so it seemed I had Celiac, so I continued being wheat/gluten free.

    After reading about how difficult it was for people because of the cravings, I searched for gluten free substitutes for baked goods and pasta. They were pretty expensive online, and that's not factoring in shipping prices. So I thought I'd tough it out if I got the cravings.

    I did get them. It was rough for about 2-3 days, then faded a little. Watching TV didn't help either! I decided to try out some local health food places and found one that carried a nice selection of gluten free baking mixes and pasta.

    My husband almost laughed as I fought off tears when I ate gluten-free muffins, after eating NO muffins for at least a month.

    And eating those gluten-substitute baked goods and pasta DID help reduce my cravings! So I'm guessing that once I past the rough first few days, maybe I was craving foods I used to enjoy but could no longer eat.

    Although Dr. Davis warns about gluten-free products still being high-glycemic and spiking blood sugars, I'm still suggesting that if you're not diabetic, and want an easier time going off the wheat, try gluten-free products to see if they offset your cravings, for it might be a combination-craving of both gluten, as well as comfort foods. After a few weeks off the gluten altogether, then wean down the gluten-free products if needed for normalizing blood sugars, weight-loss, and not spending so much on expensive gluten-free products.

    Meanwhile, my gluten-intolerance bloodwork returned negative! It looks like it was IBS triggered by insoluble fibers in whole wheats (and some other foods). But even though I discovered I can tolerate processed flour, I don't eat nearly as much flour/gluten as I did before this experience, since my borderline A1C dropped a lot after being off wheat products.

  • Anonymous

    6/4/2009 12:47:05 PM |

    In response to the sourdough , do you have a recipe using the Kefir? Thanks

  • Trinkwasser

    6/17/2009 12:56:14 PM |

    "If you try to quit smoking, you've got "crutches" like nicotine patches and gum, Zyban, Chantix, hypnosis, and group therapy sessions. If you try and quit wheat, what have you got? Nothing, to my knowledge. Nothing but sheer will power to divorce yourself from this enormously destructive, diabetes-causing, small LDL-increasing, inflammation-provoking, and addictive substance."

    It's worse! With wheat you have friends, relatives, bakeries and especially *mothers*, pushers all

    grrrrr

  • jpatti

    7/24/2009 11:57:04 AM |

    I've done induction to go back to low-carb several times when I'd gotten off track.  For me, it does feel like a withdrawal, and I tend to feel sick 2-3 days if I do it strictly, whereas otherwise I feel crappy for a week.

    I choose a time when my life will be relatively low-stress, roast a whole turkey and buy a bunch of pepperoni for snacking on.  Going meat-only for a few days makes the withdrawal pass faster.  

    After a few days of turkey and pepperoni, I add back in vegetables, then a few days later dairy, then later still, low-sugar fruits.  

    IME, that's fastest way to get through the ickiness.  

    And REMEMBERING the withdrawal is the best way to avoid having to go through it again.

  • Anonymous

    12/26/2009 3:09:37 PM |

    Hi, I can’t understand how to add your site in my rss reader. Can you Help me, please Smile

  • hopeful geranium

    5/19/2010 11:27:35 PM |

    Tom, the 10-20% addicts are not the same people for every drug.
    I was junkie, speedfreak, benzo addict, alcoholic, ether sniffer for years (decades). I chain-smoked when high (lucky to be alive smoking on ether) but always went off tobacco when sober - I could never get hooked on cigarretes, never had withdrawals, don't smoke now, but if I chose to once, it would be the only time.
    Apparently 20% of people don't have the tobacco addiction gene. Most don't smoke at all, but I enjoyed changing my consciousness with tobacco while high on other things. 20% of men where I come from are red-green color blind - I wonder if this is connected to the gene for no nicotine addiction.
    Perhaps nicotine, for all its effects, didn't interact with endorphin receptors, and for addicts, there is a link? This is known to be important for determining who gets alcoholism.

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Tribute to Tim Russert

Tribute to Tim Russert

The sudden passing of news giant, Tim Russert, yesterday of sudden cardiac death struck a blow to American consciousness.

Perhaps his hard-hitting interviewing style, while making guests squirm, made him seem invincible. But, of course, none of us is invincible. We are all vulnerable to this disease.

We should not allow Mr. Russert's tragic death to occur without taking some lessons. The media have already resorted to interviewing prominent doctors for their opinion.


Douglas Zipes, M.D., former President of the American College of Cardiology,was quoted in the media:

"An automated external defibrillator (AED) could have been a life-saver. AEDs should be as common as fire extinguishers."

This is typical sleight-of-hand, medicine-is-too-complex-for-the-public-to-understand sort of rhetoric that is surely to issue from the conventionally-thinking medical people and the press. Instead, let's cut the BS and learn the real lessons from Mr. Russert's needless death.

It is virtually certain that:

--Mr. Russert ruptured an existing coronary atherosclerotic plaque, prompting rhythm instability, or ventricular fibrillation.

--Making automatic external defibrillators (AED) available might have Band-Aided the ventricular fibrillation, but it would not have stopped the heart attack that triggered it.

--Though full details of Mr. Russert's health program have not been made available, it is quite likely that he was prescribed the usual half-witted and barely effective panoply of "prevention": aspirin, statin drug, anti-hypertensive medication. Readers of The Heart Scan Blog and members of Track Your Plaque know that this conventional approach is as effective as aspirin for a fractured hip.

--It is highly unlikely that all causes of Mr. Russert's heart disease had been identified--did he have small LDL (it's certain he did, given his body habitus of generous tummy), Lp(a), low HDL, pre-diabetic patterns, inflammatory abnormalities, vitamin D deficiency, etc.? You can be sure little or none of this had been addressed. Was he even taking simple fish oil that reduces the likelihood of sudden cardiac death by 45%?

--Far more could have been done to have prevented Mr. Russert's needless death. And I don't mean the idiocy of making AED's available in office buildings. I'm talking about preventing the rupture of atherosclerotic plaque in the first place.

Far more can be done to prevent future similar deaths among all of us.

Our jobs are to use the tragic death of Mr. Russert to help those around us learn that heart disease is identifiable and preventable. Though Mr. Russert did not stand for BS in his political commentary, he sadly probably received it in his health advice. Don't let this happen to you or those around you.

Comments (11) -

  • Anonymous

    6/14/2008 2:09:00 PM |

    Amen to everything you said Dr. and one other point I heard a nimber of times yesterday, everybody was in shock because Mr. Russert had just had a stress test done in April and passed with no problems ! As all your readers know what a stupid thing to say.

  • lenjoe

    6/14/2008 8:59:00 PM |

    Dr Davis,
    I appreciate your posting on Tim Russerts passing.  I was a big fan of his. I believe if he had worked half as hard on his heart health as he did on his career we would be enjoying him on TV for many years to come.  Of all the commentators discussions since his passing, the most important things aren't being discussed.  His diet (low fat I'd guess), his meds (statins I'm sure)...He did have a good stress test April 29.  Lot of good that did.

  • Anonymous

    6/15/2008 12:00:00 AM |

    Russert had both CAD & diabetes.

    Newsweek health article about Russert and sudden cardiac arrest:

    http://www.newsweek.com/id/141450?from=rss

    Usual blather about not being able to prevent/predict sudden cardiac death, risk factors, and usefulness of defibrillators, etc.

  • The Daley Planet

    6/15/2008 12:33:00 AM |

    Thank you for this commentary.
    His passing is very sad.
    My uncle had the same thing happen at a relatively young age as well.

    By the way, can you suggest a fish oil for those of us whom are allergic to shellfish?
    I've heard we can use any type of fish oil; just not krill oil.
    Does Sam's Club Maker's Mark fall under that category?

    Thank you!

  • Mike Donovan

    6/15/2008 3:33:00 AM |

    Regarding the death Of Tim Russert:

    In the new issue of Newsweek, Dr. Steven Nissen, chair of cardiovascular medicine at the Cleveland Clinic told the magazine when asked about the role of STRESS and heart attacks:

    "Most of us do not think it is terribly relevant," and explained this with a shocking lack of logical thinking: Newsweek writes, "After all, he notes, "many people in this world have stressful jobs," and they don't all die of of heart attacks.

    Time Magazine named Dr. Nissen one of the 100 Most Influential People In The World in their "Scientists and Thinkers" section.

    Think about that.

    Now, consider the completely illogical statement from Dr. Nissen bolded above. One thing should be made perfectly clear in light of this statement: He believes cholesterol as very relevant to heart attack risk. Yet, to turn his Newsweek comments around, "many people in this world have **high cholesterol**" and they don't all die of heart attacks.

    In fact, study after study shows countries with the highest rates of fat intake and the highest average cholesterol rates have the lowest incidence of heart disease. Imagine that!

    Dr. Nissen's irresponsible and illogical comments in Newsweek shows - again - the complete bamboozlement the cholesterol hypothesis has on western medicine just because, "everyone knows," high cholesterol causes Coronary Heart Disease. How do they know this? "Because everyone knows." Ad nauseum. With a little research, the facts show this is simply not true.

    What Dr. Nissen said about stress can be said about high cholesterol. Plenty of people live with both without having heart attacks.

    Maybe Mr. Russert's death can help in bringing us back to real science as opposed to what Big Pharma dictates as what is science - and what is not. Follow the money.

    How ironic that it was Dr. Nissen who made such a horrible misstep in logic with his comments to millions of readers in Newsweek.

  • Henry Fielding

    6/15/2008 11:00:00 AM |

    I have a couple of questions that were put to me about Heart Scans that I can't answer. Perhaps you will indulge me.

    First, from a Doctor friend of mine:  Most of the widely used diagnostic tests have been studied with respect to their Specificity, Sensitivity, positive and negative predictive value, etc. We know how to use them, and we know how to interpret the information they provide. Last I read, there is not enough correlation between the amount of calcium present in the walls of the coronary arteries, and the degree of coronary sclerosis. Maybe in time there will be enough convincing data - but for now, it is wrong to blame the slowness of the acceptance of the test by the medical community solely on financial interest.

    Second, from another friend:

    I had the EBT test and showed a calcium score of 950. An angiogram showed no blockage. Go figure. The Doc thinks the calcium is in between the artery walls with the lumen free.

  • Dr. B G

    6/15/2008 5:02:00 PM |

    Russert traditionally appeared on Charlie Rose right before Father's Day.  They were good friends -- Rose sold his house in Washington DC to him and aired a moving tribute the night after his sudden MI.

    Russert loved his father and wrote a famous book about him 'Big Russ'. It is ironic his own death was right before Father's Day today. And so much much more awful for his surviving son whom he loved so much and was very vocal about.

    I hope a new movement for cardiovascular and diabetes prevention may be sparked over this needless, rescue-able, tragic event.

    He touched so many lives... fathers, Buffalo fans, media, political enthusiasts...

    (I'm glad my Dad is aware of Track Your Plaque -- Thank you Dr. Davis... and Happy Father's Day!)

    -G

  • Dr. William Davis

    6/15/2008 9:36:00 PM |

    Mike--

    Thank you for your thoughtful and insightful comments. I coudn't agree more.

  • Dr. William Davis

    6/15/2008 9:38:00 PM |

    Henry--

    I'm sorry, but if friend told you that, you need new friends.

    The literature exists and there's quite a bit of it. Just because your friend is completely ignorant of a body of scientific literature several thousand studies long does not mean that it doesn't exist.

    All of your questions can be answered on the www.trackyourplaque.com website.

  • Henry Fielding

    6/15/2008 9:40:00 PM |

    I buy my Fish Oil from Costco. It happens to be Nature Made 1200mg softgels. Don't let anybody worry you about mercury content on this kind of product. None of these brands have any in them.

    If it causes any problems, take it with food.

  • buy jeans

    11/3/2010 2:23:19 PM |

    --Far more could have been done to have prevented Mr. Russert's needless death. And I don't mean the idiocy of making AED's available in office buildings. I'm talking about preventing the rupture of atherosclerotic plaque in the first place.

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How far wrong can cholesterol be?

How far wrong can cholesterol be?

Conventional thinking is that high LDL cholesterol causes heart disease. In this line of thinking, reducing cholesterol by cutting fat and taking statin drugs thereby reduces or eliminates risk for heart disease.

Here's an (extreme) example of just how far wrong this simpleminded way of thinking can take you. At age 63, Michael had been told for the last 20 years that he was in great health, including "perfect" cholesterol values of LDL 73 mg/dl, HDL 61 mg/dl, triglycerides 102 mg/dl, total cholesterol 144 mg/dl. "Your [total] cholesterol is way below 200. You're in great shape!" his doctor told him.

Being skeptical because of the heart disease in his family, had a CT heart scan. His coronary calcium score: 4390. Needless to say, this is high . . . extremely high.

Extremely high coronary calcium scores like this carry high likelihood of death and heart attack, as high as 15-20% per year. So Michael was on borrowed time. It was damn lucky he hadn't yet experienced any cardiovascular events.

That's when Michael found our Track Your Plaque program that showed him how to 1) identify the causes of the extensive coronary atherosclerosis signified by his high calcium score, then 2) correct the causes.

The solutions, Michael learned, are relatively simple:

--Omega-3 fatty acid supplementation at a dose sufficient to yield substantial reductions in heart attack.
--"Normalization" of vitamin D blood levels (We aim for a 25-hydroxy vitamin D level of 60-70 ng/ml)
--Iodine supplementation and thyroid normalization
--A diet in which all wheat products are eliminated--whole wheat, white, it makes no difference--followed by carbohydrate restriction.
--Identification and correction of all hidden causes of coronary plaque such as small LDL particles and lipoprotein(a)

Yes, indeed: The information and online tools for health can handily exceed the limited "wisdom" dispensed by John Q. Primary Care doctor.

Comments (32) -

  • Jan

    8/17/2011 6:36:25 PM |

    Time to stop bashing primary care docs, doc. Online sites are full of B.S.
    Show me the evidence that testing with CAC improves outcomes (Sure it predicts risks, not the same as actually preventing disease, especially in those at lower risk of CAD.)

  • Might-o'chondri-AL

    8/17/2011 8:11:19 PM |

    Hi Jan,
    Since you accept plaque showing up as being a cardio-vascular risk factor then if Doc reports he has treated some patients whose measurement of plaque has diminished using his protocol would you also accept the proposition that those patients have reduced one of their cardio-vascular risk factors?
    If Doc has patient records showing diminished plaque and therefore one less risk might that not be considered preventative due to his patient following his protocol ?
    As for those individuals with hypothetically lower risk of CAD (ex: the 63 year old low cholesterol example Doc gave) are they not going to undergo changes as they age ?  
    A primary care physician is valuable and yet older westerners are increasingly engaging specialists for good reasons.  Doc has a self-professed specialty tracking plaque  that he wants to impart; sure, his blogging tone may not always be mellow.

  • Jan

    8/18/2011 2:52:13 AM |

    Dear Might,
    Your comment is akin to those who report the association of statin use with lowered risk of MI. A correlation does not prove causation until valid  scientific research confirms.
    How do we know treating CAC lowers risk of MI until a study proves this? Docs have been wild to accept the association of statin use lowering cholesterol components as the mechanism of effectiveness for prevention of MI, ignoring studies in which dietary measures that did the same were ineffective. Just pointing out the need for caution in going so far as to treat a test without evidence that the intervention is working on the test findings (rather than something else).
    Perhaps there are studies that are underway or perhaps the evidence, er association, is just considered too strong, (Bradford-Hill criteria) to ethically justify a trial. My concern is for individuals who score in the lower range of abnormal. At what cost do we label and treat those?

  • joel oosterlinck M.D.

    8/18/2011 9:21:42 AM |

    just remembret the lyon heart study, by  Renaud & de Lorgeril demonstrating the efficacy  of mediterranean diet in lowering the risk of recurrent MI in French patients. although cholesterol levels were higher with diet than with statins. Dietary measures seem there to demonstrate  efficacy

  • Dr. William Davis

    8/18/2011 12:15:43 PM |

    Not only is it NOT time to stop bashing primary care docs, but it's time to begin accepting that their role is outdated. In fact, an average nurse practitioner or physician's assistant can do an equal, if not better, job than most primary care physicians. How health care is dispensed is going to undergo dramatic transformation, just as the business of travel agents and real estate have been transformed by rapid information exchange.

    In our program, we see virtually NO heart attacks. Not a randomized clinical trial, but watching heart attacks drop from a weekly event to almost never is good enough for me to not accept the status quo and continue to work along a path that, from every indication, works exceptionally well.

  • JC

    8/18/2011 12:49:19 PM |

    If high crab diets are considered unhealthy then why do some cultures like the rural Chinese live long healthy lives on nearly 100% crabs,mostly rice and vegetables?

  • majkinetor

    8/18/2011 2:16:50 PM |

    Isn't the best thing for calcium on wrong places vitamin K2 ?
    In my country doctors even prescribe it for calcification issues.
    Dose is around 100mcg/day for 6-12 mo.

  • Marlene

    8/18/2011 4:06:07 PM |

    Read Gary Taubes' "Good Calories, Bad Calories" to find several instances of other cultures eating the typicial high carb food yet seemingly stay within the healthy range.

  • Jan

    8/18/2011 4:22:12 PM |

    Trust my care (or a family members care) to a NP or PA who does not have the capability of complex medical decision making - no thanks. NP's actually are complimentary to physicians with different skill sets. So glad to know your level of knowledge about them. PA's are nothing but junior medical students with enormous salaries. Working 9 to 5 - oh, yeah!

    I'm certain your referral network of primary care docs would be interested in your belief system.

  • Joe

    8/18/2011 4:49:51 PM |

    Dr. Davis:
    I don't know if you've seen this new video yet, but I think you'll want to.
    http://www.youtube.com/watch?v=3vr-c8GeT34&feature=player_embedded
    If you do watch it, I have a question. This doctor thinks sugar (by itself) plays a huge role in causing plaque to rupture and cause heart attacks, etc. If after watching the video you agree with him, would you please tell me how (biologically) it does this?
    Thanks!

    Joe

  • Might-o'chondri-AL

    8/18/2011 8:51:08 PM |

    Hi Jan,
    True correlation does not necessarily equate to causation. As for statins, it seems that statins act to lessen inflammatory processes; and it is this dynamic, rather than numerically lowering cholesterol, that is a crucial way that statins correlate with reduced risk. Which, to me,  seems to further support Doc's contention here in this posting that  low cholesterol levels doesn't  tell one if they have abnormal plaque (ex: patient above with "exceedingly high" score) .

    I will accept Doc's data, as given ,that very high plaque is a 15-20% risk factor since many other published sources cite even carotid plaque as a risk factor . As far as who to test for what, and when, I am not qualified to make recommendations. I do know that time can remodel some cellular dynamics and the aging cardio-vascular system is vulnerable to alterations.  Doc's got my attention because no one at all in my paternal male ancestral line lived past their late 50's due to heart problems and I am 60; while my 61 year old brother already was hospitalized from transient ischemic attack  .

  • Might-o'chondri-AL

    8/18/2011 9:33:17 PM |

    Mediterranean diet's efficacy for heart health is probably due to the % of poly-amines per calorie consumed and of course isn't in keeping with Doc Davis' detestation of modern wheat (among other protocols). As we age our poly-amine levels decrease and Mediterranean diet supplies lots of poly-amines.

    Poly-amines ( molecules inelegantly named spermine, spermadine and putrescine) are all anti-inflammatory, especially spermine; in our body we synthesize poly-amines from arginine. Mediterranean diet's high poly-amine levels spares the amount of arginine our body uses in synthesizing poly-amines; and thus we can more readily produce the vaso-dilator signalling molecule NO (nitric oxide) from body's arginine. NO is valuable to keep oxygenated blood reaching the heart muscle cells; NO keeps vessels from constricting dangerously.

    Poly-amines lower inflammation and in the context of age associated problems the less low grade inflammation the better.  Inflammation leads to defectively functioning cells and molecular processes; with time the  over stimulation of immunological responses (both innate and adaptive immunity) leaves the body burdened with unknown clones of T cells (both memory and effector types). Eventually the build up of  T cell clones limits new variants and what occurs is more macrophages circulating; once an over abundant macrophage stage reins the body is essentially always in low grade inflammation , and prone to various age associated pathology (including cardio-vascular).

  • Dr. Johns

    8/19/2011 12:25:40 AM |

    @jan....
    A vast majority of primary care doctors are extremely limited in their abilities to treat/advise patients for CVD risks. They don't understand nutrition, effects of supplements upon serum biomarkers, nor effective diagnostic testing for heart disease.
    CAC is a much better biomarker for who is at greater risk of CVD than serum markers:
    http://www.eurekalert.org/pub_releases/2011-08/jhmi-sfc081611.php

    I seriously doubt even 1:100 primary care docs see studies like the aforementioned one.
    And I seriously doubt the one doc would understand it....
    Dr. John

  • Gene K

    8/19/2011 1:48:19 AM |

    An interpretation of the same study for a broader audience just appeared at http://www.webmd.com/heart-disease/news/20110818/is-calcium-test-the-best-way-to-check-for-heart-risk.

  • Thomas White

    8/19/2011 2:09:49 AM |

    I'd accept a bashing of physicians in general.   But to single out primary care physicians - overwhelmed with paperwork and patients with multiple problems, and vastly underpaid and underappreciated, and continually put down by "Partialists" - Really ? Cardiologists are superior? Really ?

    Forget my support and admiration henceforth.

  • Might-o'chondri-AL

    8/19/2011 5:43:43 AM |

    CRP (C-reactive protein), an inflammation marker surrogate, does not directly correlate with whether there is coronary artery calcium (CAC), or the degree of CAC severity. CRP is also subject to variables of race and age, so it loses some potential as a predictive marker. Yet looking at CAC along with CRP is considered useful for complex insight into a patients pathology.

    Analysis of the Multi-Ethnic Study  of Atherosclerosis (MESA) involving 6,800 men & women seems to indicate that inflammatory markers (ex: CRP) relate to the physiology of pathological processes other than CAC laid down; possibly because plaque undergoes morphological changes over time. The CRP level is proposed, by some, to relate more to the stability of plaque from rupturing and the incidence of blood clotting in a thrombosis.

    The inflammatory marker of Interleukin-6 (IL-6) anti-bodies seems to be better than CRP and fibrinogen for correlating an individual's trend toward CAC. Thus the cytokine IL-6 is a better indicator of sub-clinical atherosclerosis; Doc likes to cut to the chase, eyeball the plaque and track it with current technology ( that is not available worldwide).

  • David

    8/19/2011 6:16:33 AM |

    Is it typical for someone with such low ldl and high hdl to have such a high CAC score? Had he previously had a higher LDL and then been placed on a statin?

  • TT

    8/19/2011 12:36:37 PM |

    The energy expenditure of the rural Chinese is very high.  They don't drive, they walk, or ride bicycles.  They don't sit in office from 9am to 5pm, they work hard in the rice field from 5am to 9pm.  They can eat anything without gaining weight.
    For the urban Chinese, it is a different story.  They have the same life sytle as ours, and they are getting heavier every year.  More and more people become diabetic, even young kids.

  • Dr. William Davis

    8/19/2011 1:51:32 PM |

    K2 is indeed a fascinating nutrient. There are extensive discussions about it on the Track Your Plaque website.

  • Dr. William Davis

    8/19/2011 1:53:33 PM |

    Thanks, Joe. I watched the entire thing and was impressed with Dr. Diamond's grasp of the issues.

    I'm going to post this on the main page because I think his overview was extremely effective.

  • Dr. William Davis

    8/19/2011 1:55:24 PM |

    Sorry you see it that way. This was a comment directed at the system of primary care in general.

    I reread the post and I didn't see the name "Dr. Thomas White" mentioned anywhere. If you choose to feel slighted in some way, that's your choice.

  • Kent

    8/19/2011 3:20:32 PM |

    Jan, I would certainly trust my care (or a family members care) to a NP or PA who looks outside just the pharma driven medical journals which primarily support a diagnose & drug philosophy.  And I'll take an NP or PA who actually uses some common sence rather than being a puppet given to the pushy drug rep.

    I live in a family of MD's, and they have made it clear as to their terribly limited training and knowledge they gain from med school on the level of building and supporting the body from within.  Example, I have an Aunt that is currently suffering from stage 4 cancer. Due to the chemo treatment that she's instructed to not spend time in the Sun. Her Dr. has not even checked her for vitamin D levels. This is not the exception, but the norm when it comes to common sence treatment, pathetic.

  • Joe

    8/19/2011 6:56:14 PM |

    Okay, Dr. Davis.  I'll be looking for it. When you do, please take a moment and explain how you think that sugar might be responsible for plaque rupture.
    Thanks again!

    Joe

  • steve

    8/19/2011 7:06:59 PM |

    Sugar is just one part of the equation.  As Dr. Davis has covered on this website, small LDL is also a villian and needs to be minimized as much as possible.

  • Might-o'chondri-AL

    8/19/2011 8:05:24 PM |

    Hi Joe,
    Thanx for the video ... maybe the following answers you.

    Regarding sugar: see 59:33 into presentation, where diagram shows "sugar" blurb  - lecturer is using compact word sugar to represent how glucose's glycation end products alter the artery and make the artery vulnerable. It is not a molecule of sugar acting all by itself; lecturer explains slide when talks of how glycation is a problem (another of  Doc Davis'  peeves).

    Follow up at 1:01 into presentation: see diagram's top left  where the various adverse influences on artery  are specified as "modified lipoprotein", "hemodynamic insult" (includes, but is not limited to blood sugar's  glycation end products affect on artery), "reactive oxygen species" (ROS) and "infectious agents".

  • Thomas White

    8/20/2011 12:22:15 PM |

    Thank you for all your hard work and dedication to your web site and education.

    I apologize for cluttering up the discussion with a personal statement.

    TRW

  • Joe

    8/20/2011 4:13:56 PM |

    Thank you, Might. I guess I'm going to have to do some research on glycation before I can fully understand what you're saying above.

    I didn't even notice the PowerPoint Presentation that was included with Dr. Diamond's video presentation.  Sigh.

    Thanks again!

    Joe

  • Jim

    8/20/2011 7:55:03 PM |

    AMEN! Right on target.

  • Louis

    8/23/2011 2:05:01 PM |

    I don't know if you're aware of the differences between calculated test that most doctors use and NMR that Dr. Davis uses. When your diet consists of mostly carbohydrates leading to chronic high blood sugar level, it tends to raise your SMALL DENSE LDL level but calculated cannot measure it accurately. It often greatly underestimate it.  Dr. Davis has covered it many times. Dig through his website for it.

  • Louis

    8/23/2011 2:16:27 PM |

    Optimal vitamin D level helps lower IL-6. It can be a big problem with black people as they tend to have the lowest vitamin D level of any races. Dr. Cannell mentioned that in his new book called Athlete's Edge Faster Quicker Stronger with vitamin D with the hope that the word about vitamin D would spread out faster if more and more professional athletes started using it to gain some advantage over opponents much like what East Germany and formerly USSR used to do in 1960 and 1970s at the Olympic games and other world events.

  • live-healthcare

    8/27/2011 4:31:48 AM |

    Yes Joe i have seen the video you linked. That's right i also think the same.

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