People like you and Dr. Eades have my complete respect precisely because you're not only willing but eager to adjust your advice in accordance with your understanding of the latest and best science.  Like you, Dr. Eades is constantly pointing out where he's adjusted his recommendations, whether from an earlier book or even just an earlier post.

Contrast that behavior with the latest diet study where Bray et al attempted to pass off a diet including daily rations of bagels, pasta, and bananas as "low carb."  How sad, how grotesque authority figures are when they cling to a pretense that there is nothing for them to learn!  And they led Harvard University, the New England Journal of Medicine and most of the "health" writers in the nation right into the briar patch!

Another thing to consider adding to the new book is something about periodontal/gingival disease which is a constant source of inflammation in the body leading to elevated CRPs.

Anonymous
Low 25(OH)D is associated with periodontal disease
http://www.ajcn.org/cgi/content/full/80/1/108
Just reading the list of VDR sites here
http://www.ncbi.nlm.nih.gov/pubmed/18777944 Vitamin D and the digestive system should be sufficient for people to realize it   may play a major role in our ability to deal with inflammation.

Dr. D., the Dr's. Eades have shaped my thinking about diet more than any other source, specifically their emphasis on carbohydrates and the  role of insulin in  disease.  I am thrilled that you admire each other, thus confirming my intuition about the worth of each of your approaches.  I also judge you and the the Eades to be of the highest caliber as debunkers. I may never meet any of you, but you are the team I regard as my primary health advisers, along with Dr. John Cannell.  May you all thrive, and may many others learn from you and thrive as well.  Though I found the Eades in the book store many years ago, I am so grateful that the Internet now provides us all with such a valuable tool to work for our own well being.  The more successful we all are  in this enterprise, the sooner our health care becomes truly our own, and the better it will be.  Onward!

seems to me that if you are far away from TYP goals of 60/60/60 that you should through diet/nutrition supplements just work towards those goals.  Why not just get frequent NMR tests and avoid any level of radiation?

I was born and brought up on newsgroups, used various forums and came late to the blogosphere. To you and the estimable Michael Eades I'd add Mark Sissons and Hyperlipid as must-reads. You all come at the same conclusions from different perspectives, and keep up with current work.

Your readers would like this

http://high-fat-nutrition.blogspot.com/2009/02/cholesterol-presentation-between.html

Hi Dr. Davis.  
Another blog you may want to check out is "whole health source."
His latest post is about a recent study examining the effects of Vitamin K on heart disease.  Here's the link:

http://wholehealthsource.blogspot.com/

What if spaghetti sauce is NOT made with HFCS? I love my spaghetti sauce over my chicken.......in moderation.

Nice find.... this really demonstrates the insidious nature of HFCS, on multiple fronts.

Dr. Ron Krauss again.  Any research with his name on it is superb in my book.  I wonder if he knows Dr. Lustig (UCTV Fructose lecture).  They are neighbors.  So is BG.  Thanks for the whole reference.

Dr. Davis,

Given this information. If someone has a good BMI and good overall diet without grains, how much fruit should they limit themselves to in a day. Should they only eat this fruit with a meal and not eat it alone between meals?

Is Grazing on protein and vegetables also bad?

Thanks,
Penny

Wow. I guess fructose of any source would be bad, not just HFCS but eating an apple as well? It's hard to rationalize why something that is found in nature, is a whole food, and appeals to our sense of taste, would be bad for us. Maybe the fact that the fructose in the the study was in liquid form, versus being held up in some fiber, had something to do with the results but this isn't the first time that I have read that fruit is bad for you.

Keep in mind that the design of studies like this are often meant to yield exagerrated effects for the purposes of clean observations. It does not necessarily mean that every time you eat, you get similar postprandial phenomena.

Nonetheless, I believe there are important lessons from such studies.

This study suggests that a rice cracker or a potato (converted directly to gluclose) might be more healthful than a piece of fruit

I've been able to adapt relatively easily to everything in your TYP program Dr. Davis, but this one seems to be the toughest for me.

I don't think I can eat one meal a day.  I have always been blessed with a fast metabolism and need at least 3,000 (LC) calories even on a moderately active day, or I start to lose weight, which at 5' 9" 165# @ 8% BMI, I don't want to do, and probably shouldn't.

3,000 calories is simply too much for me to eat in one meal.  Plus, it seems so counter-intuitive to good health, like maintaining a good energy/thermogenic/glucose/insulin/nitrogen balance throughout the day.  It just seems a perfect recipe for storing fat at the expense of lean mass, which is the complete opposite of paleolithic man's highly muscular, lean composition. I don't know, maybe just I wouldn't survive well back then...

This is an excellent point- the reverse of intermittent fasting and variation in calorific consumption. Excess macronutirent calories, in the wrong form, at frequent intervals. No surprise there are adverse implications. OB

It rings a bell. My maternal grandfather died not long after a meal.

Re fructose from fruit vs HFCS, I don't think that there's much comparison.

There are benefits to eating fruit (antioxidants, fiber, vitamins).  There is no benefit to consuming HFCS.

Choose your fruits carefully and eat in moderation...

I doubt that eating fruit is the same as eating refined fructose.  Not all fruit is high in fructose, for instance.  Also, the fiber in the fruit slows absorption, and this may give time for the fructose to be fermented by bacteria in the gut, producing, for instance, acetic acid, which may be beneficial to fat deposition patterns. (This is just a personal theory of mine.)  

Furthermore, fruit contains vitamins, minerals, antioxidants, and flavoniods, which can benefit glucose metabolism, prevent lipid oxidization, and dampen the tide of free radicals and advanced glycation end-products (AGEs) produced by glucose and fructose metabolism.

Those concerned with the effects of fructose from fruit should focus on eating whole fruits only (no juice), and eat mostly berries (low in fructose, high in flavonoids).

I think it would be wise to separate the valid concerns about refined fructose from fruit.  We could be as off-base about vilifying fruit as people were about eggs.

Just because a food contains a substance that can is harmful when it's been refined from its source doesn't mean that it has the same effect when found in a whole food.  The digestion and metabolism of whole foods is far more complex than can be understood by studying a single factor.

If it's something humans have eaten for millennia, and it's safe to say that fruit is, I think it's probably innocent until proven guilty.  Just don't eat refined stuff (including juice), and you'll be fine.

I am now trying to eat a diet that is very low in carbohydrates, moderate in protein, and high in fats like butter, omega-3 eggs, and cream cheese.

This kind of diet seems to prevent the blood glucose spikes and the very unpleasant tachycardia that I get from high-carb meals.

And it is frequent small meals that best control my blood glucose and the tachycardia.

Pmp--

Eating once a day was not the intended message.

This discussion is simply part of a larger discussion on the effects of various foods on postprandial patterns. We must all eat and preferably do so 3 times a day.

Good one on "Postprandial pile-up with fructose".I'm using the methods from http://debtfreeliving.lose20.com to reduce weight and it really works.

Thanks,
Edwin-   Lose 20 - Losing weight may save your life

Hey, not all  spaghetti sauce has added fructose. Those made with sugar and or fructose cost more, because they are cheating on the ingredients.

And yes, sugar is (half) fructose.

Dr. William Davis, do we have any studies that show 3 times a day is optimal? One could hardly do a double blind study on this.

I ate 50 grams of grapefruit (with extra fiber), with my last meal of the day and it spiked my blood sugar from 120 to 170 in 1 hr and I think I felt the beta cell damage for several hours - fruit is worse than oatmeal WITH sugar! I am pre-diabetic. I am trying to give up all bad things, but I am starving and I have to eat. I have chewing problems, so this complicates things. I tried soymilk, but it seemed to destabilize me, which is not good - I'll try it with fiber next time. I am underweight now. I am in a real bad place. I can't eat fruit anymore and even veggies give me problems. I hope I can avoid scurvy. Does anyone know if vitamin C pills truly prevent scurvy?

I don't think I can eat one meal a day. I have always been blessed with a fast metabolism and need at least 3,000 calories

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