Fish oil makes you happy: Psychological distress and omega-3 index

For another perspective on omega-3 blood levels, here's an interesting study in northern Quebec Inuits.

Traditionally, Inuits consumed large quantities of omega-3-rich seal, fish, caribou, and whale, even eating the fat. However, like the rest of the world, modern Inuits have increased consumption of store-bought foods, largely processed carbohydrates. Along with this trend has emerged more heart disease, diabetes, and depression.

A group from Laval University and University of Guelph, both in Canada, examined the relationship of plasma EPA + DHA levels and measures of psychological distress. This group had previously shown that Inuits older than 50 years had twice the plasma omega-3 levels (11.5%) compared to those younger than 50 years (6.5%), reflecting the shift away from the traditional diet.

Psychological distress was measured with The Psychological Distress Index Santé-Québec Survey (PDISQS-14): the higher the score, the greater the psychological distress. (In the graphs, tertile 1 is least distressed; tertile 5 is most distressed. Sorry about the small chart graphic--click on the graphic to make it bigger.)


From Lucas M et al 2009 (http://www.nutrasource.ca/NDI/Assets/Articles/Plasma%20omega-3%20and%20psychological%20distress%20among%20Nunavik%20Inuit.pdf)

"Our main finding was that women in the second and third tertiles of EPA+DHA concentrations in plasma PLs [phospholipids] had a 3 times lower risk of having a high-level PD [psychological distress] score than women in the lowest tertile."

While the relationship is stronger for women, you can see that, the higher the EPA + DHA plasma level, the lower the likelihood of psychological distress. Interestingly, the tertile with the greatest distress and lowest EPA + DHA levels had a plasma level of 7.0-7.5%--far higher than average Americans.

(Plasma levels of EPA + DHA were used in this study, which tend to reflect more recent omega-3 intake than the more stable and slower-to-change RBC Omega-3 Index that we use. Plasma levels also tend to run about 10-20% lower than RBC levels.)

Of course, there's more to psychological distress than omega-3 blood levels. After all, eating fish or taking fish oil capsules won't make money worries go away or heal an unhappy marriage. But it is one variable that can be easily and safely remedied.

Comments (24) -

  • Boris

    10/30/2009 1:31:07 PM |

    I think your are on to something, Dr. David. Every winter I get sad and depressed. After starting my omega-3 supplements, I noticed that I started feeling "better". I know that's very subjective. We set our clocks backwards 1 hour in a few days. I guess I will get a chance to test the "happy factor" of fish oil soon!

  • Rob McVey

    10/30/2009 2:14:08 PM |

    FYI, Laval is in Quebec, but Guelph is in Ontario (albeit both Canada). Perhaps you'd edit the post.
      --  Rob McVey, Markham, Ont.

  • Haggus

    10/30/2009 3:02:22 PM |

    Just to make it clear, the Univesity of Guelph is located in Ontario.

  • Jim Purdy

    10/30/2009 3:25:04 PM |

    I live in a high-rise apartment building where many of the residents are grouchy old ladies.

    Should I sneak fish oil into their food?

    Or should I move into a building with lots of happy old Inuits?

  • Deb

    10/30/2009 3:27:52 PM |

    I always enjoy and learn so much from you blog. Thank you.
    I have tried taking omega 3 fish oil capsules but they give me acid stomach and fish burps. Any solution to these problems? I have tried the enteric coated ones too.

  • William Trumbower

    10/30/2009 4:13:28 PM |

    I am not surprised at this data.  When I began taking adequate fish oil (7gm EPA+DHA) I noticed an improved mood, memory, and ability to organize my activities.

  • Dr. William Davis

    10/30/2009 5:00:07 PM |

    Rob and Haggus--

    Thanks for the correction.

  • Dr. William Davis

    10/30/2009 5:00:37 PM |

    Hi, Jim--

    Perhaps throw a fish oil party for the ladies!

  • Boris

    10/30/2009 6:13:55 PM |

    Deb,

    You are experiencing the effects of "cheap" fish oil that has a lot of other stuff in it besides Omega-3. I tried Walmart's Nature Made stuff and it made me feel sick. Now I am take Omapure 4x a day (one capsule each time) and I do not feel the same "fishy" burps.

  • Rich S

    10/30/2009 6:48:34 PM |

    Deb-

    Try lemon-flavored liquid form of EPA/DHA. Go with a high quality brand like Carlson, which a lot of us use.

    One tsp gives you 800EPA+500DHA (1300 total), and it actually tastes pretty good (it's not cod-liver oil).

    Buy it online, such as from i-Herb as an example:

    http://www.iherb.com/The-Very-Finest-Fish-Oil-Lemon-Flavor-16-8-fl-oz-500-ml/2796?at=0

    You won't have to swallow all those softgels, which used to bother me.  Also, a good quality distilled fish oil should not cause gastro distress, etc.

    Rich

  • Nameless

    10/30/2009 7:24:58 PM |

    They have done Omega 3 depression studies. I believe they found EPA more important than DHA for improving depression scores. A lot of the 'mood' fish oil supplements tend to be EPA heavy too.

    I think they theorize that EPA helps the brain function, while DHA is primarily for structure (hence why it's important for children/babies).

  • Anonymous

    10/30/2009 8:32:51 PM |

    I think this is an important study, but I have to wonder if low omega-3 might also indicate difficult in fiding adequate food, which would clearly be stressful.  It's a chicken and egg argument so to speak.  Without verying that total nutrition other than omega-3 was adequate, I'm no sure a real conclusion can be made.

  • JD

    10/30/2009 10:37:58 PM |

    The question would be is it the Omega 3's or the fact that those who eat carbs get more depressed?

  • AuntWie

    10/31/2009 4:36:55 AM |

    I've battled depression on and off for most of my life.  Meds help.  Fish oil and lots of vitamin D help even more.  I increase my intake of both whenever my exposure to sunlight is limited (including when the summer heat keeps me indoors a lot.)

  • Anonymous

    10/31/2009 11:41:10 AM |

    So what would be the typical EPA+DHA daily dose (not the oil) to reach these heights of happiness...or plasma levels?

  • Dr Matti Tolonen

    10/31/2009 12:20:06 PM |

    Another recent report from Laval University suggests that highly purified ethyl-eicosapentaenoic acid (E-EPA) may relieve psychological distress in middle-aged women.
    The daily dosage was about 1gram.
    http://www.ajcn.org/cgi/content/abstract/89/2/641
    E-EPA is a very popular omega-3 supplement in Europe and Japan.

  • Dr. William Davis

    10/31/2009 1:32:40 PM |

    In response to several comments--

    Taken in the context of other studies, this study simply adds to the notion that omega-3 intake is associated with mood status.

    While omega-3 plasma levels may also serve as a surrogate for other phenomena, such as vitamin D intake (also rich in fish, though not fish oil), the experience as a whole do indeed show a strong relationship between omega-3 levels and depression/mood/"psychological distress."

  • Red Sphynx

    11/1/2009 2:24:01 PM |

    I'm skeptical of this study.  Look, I expect that, eventually, research will show a strong relationship between mood and LC ω-3.  But this study ain't it.

    First off, this is an observational study.  When observational studies turn up order-of-magnitude differences, they point to cause-and-effect relationships.  But when they turn up relationships that barely pass the statistical significance test (p ~ .05) they are more likely measuring the shared influence of some other cause.

    And what might this cause be?  Well, the authors point out (a) seafood consumption varies upwards with wealth and income.  (b) Happiness varies upwards with wealth and income. (c) They really would have liked to have controlled for wealth and income but they couldn't because the Inuits wouldn't fill out the wealth and income portion of the questionnaire.  

    So their study was underpowered to measure one of the most obvious non-physiological explanations of the (weak) correlation they found.

    This study would have us believe (a) Inuits have much higher ω-3 levels that other Quebec citizens.  (b) The suicide rate among Inuit in 1987–1994 was 6.5 times higher than in the rest of Québec, and the rate in the younger age group (15–
    24 years) was 20 times higher. (!!) (c) ω-3 is associated with better mood.

    Something is pretty discordant there.

    I'll wait for an intervention study.

  • Dr. William Davis

    11/1/2009 9:38:06 PM |

    Hi, Red-

    That's right.

    This study, taken in isolation, proves nothing. It only adds to the other observations that suggest that omega-3 may exert an effect on ADHD, bipolar illness, depression, etc.

    The fact that there appears to be concordance across different populations, though with differing frequencies of depession, is the argument of importance.

  • Dr. William Davis

    11/1/2009 9:38:13 PM |

    Hi, Red-

    That's right.

    This study, taken in isolation, proves nothing. It only adds to the other observations that suggest that omega-3 may exert an effect on ADHD, bipolar illness, depression, etc.

    The fact that there appears to be concordance across different populations, though with differing frequencies of depession, is the argument of importance.

  • Razwell

    1/26/2010 6:40:33 PM |

    Fish oil makes me depressed and nauseous and tired . I do not  know what all the fuss is about.

    I use a supposedly good type too, Carlson's.

  • buy jeans

    11/3/2010 10:03:25 PM |

    A group from Laval University and University of Guelph, both in Canada, examined the relationship of plasma EPA + DHA levels and measures of psychological distress. This group had previously shown that Inuits older than 50 years had twice the plasma omega-3 levels (11.5%) compared to those younger than 50 years (6.5%), reflecting the shift away from the traditional diet.

  • Lisa

    5/16/2011 9:13:39 AM |

    Omega-3 is geally great. Improves memory , I'm loosing pounds and I don't feel hungry or depressed (and when I'm depressed I eat soooo much!).  I prefer flax oil of flax seed as a sourse of omega-3.  My body seems to reject fish oil and I think it's not for nothing. The mercury pollution won't do any good.

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Dr. Nieca Goldberg and heart healthy

Dr. Nieca Goldberg and heart healthy


In January, 2007, $11.6 billion (2006 net sales) cereal manufacturing giant General Mills rolled out three million boxes of Wheat Chex and Multi-Bran Chex, each boasting a picture of cardiologist, Dr. Nieca Goldberg's face on the box.

Dr. Goldberg has been a frequent national spokeswoman for the American Heart Association (AHA). In a media interview, American Heart Association President, Dr. Alice Jacobs, stated that she supports Dr. Goldberg's work with the General Mills’ products. "The AHA is always in favor of educating the public on how to make heart-healthy lifestyle choices." Dr. Jacobs added that the AHA doesn't consider Goldberg's appearance on the cereal boxes ‘an endorsement’ of the products. "The content on the box is basic heart health information," she said.

Putting images of someone like Dr. Goldberg on cereal boxes appeals to a certain audience, mothers worried about health in this instance. Manufacturers recognize that the perceptions of their food need to be created and nurtured.

Eerily reminiscent of tobacco company tactics of the 20th century? Recall the Brown and Williamson claim that Kool cigarettes keep the head clear and provide extra protection against colds? Lucky Strike, Chesterfield, and Camels all promoted the health benefits of cigarettes, including prominent endorsements by physicians.

How about Philip Morris’ ads for Virginia Slims cigarettes: "You've come a long way, baby"? Interestingly, food manufacturing behemoths Kraft and Nabisco were both majority-owned by Philip Morris, now renamed Altria.

Take a look at the composition of these two "heart healthy" breakfast cereals endorsed by Dr. Nieca Goldberg and the American Heart Association:



























Products like this:

--Make people fat--abdominal fat (wheat belly)
--Reduce HDL cholesterol
--Raise triglycerides
--Dramatically increase small LDL
--Increase inflammatory responses
--Increase blood pressure
--Increase likelihood of diabetes

These products are sugar and sugar-equivalents with a little fiber thrown in and a lot of marketing propaganda, aided and abetted by the misguided antics of the American Heart Association and Dr. Goldberg. It's hard to believe that Dr. Goldberg would sell her soul on something so knuckleheaded for a moment of notoriety.

As I've often said, if a product bears the AHA Check Mark of approval, be sure not to buy it.

Comments (1) -

  • Darcy Elliott

    3/25/2008 6:10:00 PM |

    Thank you for your efforts on topics like this! It's just not right that supposed experts are pushing this wheat and cereal garbage. Thankfully my wife has tapped in to some really good almond and coconut flour recipes recently, I don't miss wheat at all!

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Heart disease "reversal" gives health a bad name

Heart disease "reversal" gives health a bad name

Put the search phrase "reverse heart disease" into your internet search engine, and you'll uncover an astonishing range of sites, all making extravagant promises.

The treatment programs offered range from the bizarre (colonic irrigation, magnetism, etc.), to centers using conventional approaches like statin drugs and low-fat diets, to sites that make lofty predictions with few unique tools (slash the fat and heart disease dissolves).

95% or more of the sites you turn up are clearly pandering to the unknowing, the unsophisticated, the hopeless, or other helpless niche groups. Homeopathic preparations, chelation, magnical combinations of herbals, you name it, you'll find it attached to claims for heart disease reversal.

I've seen people use many of these treatments. Is there any effect on the rate of increase of the heart scan score? Do they impact on the 30% per year expected rate of increase? Absolutely not.

Unfortunately, this gives anyone practicing truly effective methods to reverse coronary plaque a bad name. Just associating with this suspect group of "practitioners" can make us look bad--guilt by association.

Whenever someone claims to have the secret of heart disease reversal, I ask "Can you prove it?" Show me some evidence. It doesn't necessarily have to be $30 million drug company sponsored study, but some evidence of effectiveness should be available. The only thing we should take on faith is our religion, not our health care.

Our growing number of people who have, indeed, reversed their heart scan scores--reversed heart disease--to me is persuasive evidence of the value of the Track Your Plaque approach. Not foolproof, not 100%, but the best damned approach I'm aware of, by a long shot.
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Are you a skinny fat person?

Are you a skinny fat person?

AT 186 lbs. and 5 feet 10 inches, Doug did not regard himself as overweight. Sure, he had a little extra "love handles", a small bulge in the belly and a waist of 34 inches. But he was by no means fat, particularly compared to most of his friends, neighbors, and co-workers, many of whom were 50-100 lbs heavier.

But examine Doug's lipoprotein patterns and, if you didn't know what he looked like, you'd guess that he's at least 50 lbs or more overweight. His prominent patterns included low HDL, small LDL, high triglycerides, the after-eating IDL, and borderline high blood sugar of 116 mg/dl. His blood pressure usually ranged around 138/82.

In other words, Doug is among the 5-10% of people who have most of the features of the so-called "metabolic syndrome", but don't look the part. They usually (though not always) have a modest excess of visceral abdominal fat. While some people have to be 100 lbs overweight before they express these patterns, someone like Doug could do it with minimal excess weight, sometimes as little as 5-10 lbs.

Several specific genetic patterns can account for this exagerrated sensitivity to weight, but the solutions remain much the same. Heightened sensitivity to processed carbohydrates, particularly those containing wheat, is commonly present. A sharp reduction in processed carbohydrates like breads, breakfast cereals, and pretzels yields a huge benefit. Reduction in weight, of course, can also yield marked improvement in these patterns. This means that Doug should consider achieving his truly ideal weight of <175 lbs and become a truly skinny skinny person. Though his patterns might not be fully corrected, he will see substantial improvement across the board.

These patterns are also potent triggers for coronary plaque growth. Correction of low HDL, small LDL, etc. is crucial if you are to seize hold of your heart scan score.

Comments (1) -

  • buy jeans

    11/3/2010 7:01:26 PM |

    In other words, Doug is among the 5-10% of people who have most of the features of the so-called "metabolic syndrome", but don't look the part. They usually (though not always) have a modest excess of visceral abdominal fat. While some people have to be 100 lbs overweight before they express these patterns, someone like Doug could do it with minimal excess weight, sometimes as little as 5-10 lbs.

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In search of wheat: Einkorn and blood sugar

In search of wheat: Einkorn and blood sugar

There are three basic aspects of wheat's adverse health effects: immune activation (e.g., celiac disease), neurologic implications (e.g., schizophrenia and ADHD), and blood sugar effects.

Among the questions I'd like answered is whether ancient wheat, such as the einkorn grain I obtained from Eli Rogosa, triggers blood sugar like modern wheat.

So I conducted a simple experiment on myself. On an empty stomach, I ate 4 oz of einkorn bread. On another occasion I ate 4 oz of bread that dietitian, Margaret Pfeiffer, made with whole wheat flour bought at the grocery store. Both flours were finely ground and nothing was added beyond water, yeast, olive oil, and a touch of salt.

Here's what happened:

Einkorn wheat bread:

Blood sugar pre: 84 mg/dl
Blood sugar 1-hour post: 110 mg/dl

Conventional wheat bread
Blood sugar pre: 84 mg/dl
Blood sugar 1-hour post: 167 mg/dl

The difference shocked me. I expected a difference between the two, but not that much.

After the conventional wheat, I also felt weird: a little queasy, some acid in the back of my throat, a little spacey. I biked for an hour solid to reduce my blood sugar back to its starting level.

I'm awaiting the experiences of others, but I'm tantalized by the possibility that, while einkorn is still a source of carbohydrates, perhaps it is one of an entirely different variety than modern Triticum aestivum wheat. The striking difference in blood sugar effects make me wonder if einkorn eaten in small quantities can keep us below the Advanced Glycation End-Product threshold.
 

Comments (32) -

  • Jim Purdy

    6/14/2010 12:21:36 AM |

    Doctor Davis, for those of us who aren't inclined to bake our own bread, but who still like sandwiches, are there any commercially available breads (or bread substitutes) that you would recommend?

    Jim Purdy
    The 50 Best Health Blogs

  • Anne

    6/14/2010 3:19:39 AM |

    Did you check your blood sugar at 2 hours? There are times when my BG spike is later than 1 hour.

    Very interested in hearing about everyone's experience.

  • D.M.

    6/14/2010 5:43:36 AM |

    Interesting, but assuming that the einkorn bread contained the same amount of carbohydrate as conventional bread (if it contained less, then this effect is hardly magical) then one would expect a similar effect on blood sugars ultimately. Perhaps einkorn bread simply left you with higher blood sugars at three hours?

  • David M Gordon

    6/14/2010 11:35:16 AM |

    What do you think of displacing wheat in favor of coconut? The following text is a blurb for a cookbook (of all things!)...

    "Are you allergic to wheat or sensitive to gluten? Perhaps you avoid wheat because you are concerned about your weight and need to cut down on carbohydrates. If so, the solution for you is coconut flour.

    "Coconut flour is a delicious, healthy alternative to wheat. It is high in fiber, low in digestible carbohydrate, and a good source of protein. It contains no gluten so it is ideal for those with celiac disease.

    "Coconut flour can be used to make a variety of delicious baked goods, snacks, desserts, and main dishes. It is the only flour used in most of the recipes in this book. These recipes are so delicious that you won't be able to tell that they aren't made with wheat. If you like foods such as German chocolate cake, apple pie, blueberry muffins, cheese crackers, and chicken pot pie, but don't want the wheat; you will love the recipes in this book! These recipes are designed with your health in mind. Every recipe is completely free of wheat, gluten, soy, trans fats, and artificial sweeteners. Coconut is naturally low in carbohydrate and recipes include both regular and reduced sugar versions. Coconut flour pres many health benefits. It can improve digestion, help regulate blood sugar, protect against diabetes, help prevent heart disease and cancer, and aid in weight loss."

  • Jenny

    6/14/2010 12:12:46 PM |

    Dr. Davis,

    Unfortunately, all your test showed is that the einkorn digests more slowly than the other wheat. You might have seen the same result with a sourdough white bread.

    A more reliable test would have tested at 1.5 and 2 hours, but because you have normal insulin production you would have to have measured insulin to see what was really happening.

    All carb would have eventually been digested, and it takes the same amount of insulin to process it. While it's good to avoid blood sugar spikes if a person is insulin resistant the einkorn will provoke a large though slower insulin release.

    This is the problem with the whole idea of the glycemic index. If the problem is insulin, the SPEED with which it is secreted really is a red herring.

  • Anonymous

    6/14/2010 12:30:28 PM |

    What about the blood sugar level after 2 hr? 3? 4? Could it be that, like pasta, the einkorn bread gives a steady medium-high blood sugar for 3-4 hours, while normal wheat gives a spike yet quickly falls down to base level?

  • Martin Levac

    6/14/2010 12:45:29 PM |

    In my opinion, the AGE threshold is ketosis. In ketosis and there's little to no AGE production, out of ketosis and there is AGE production. Then there's the bit about ketones directly stimulating junk protein aka AGEs recycling and it becomes obvious what the threshold really is.

  • Dr. William Davis

    6/14/2010 1:14:48 PM |

    Excellent points about the delayed blood sugar response with einkorn.

    Yes, indeed. It would have to generate a longer blood glucose curve, as DM suggests, it is still a carbohydrate, though I did not specifically test this.

  • Dr. William Davis

    6/14/2010 1:15:32 PM |

    David--

    I wasn't aware of using coconut flour in place of wheat flour. Interesting!

    Have you tried it?

  • Martin Levac

    6/14/2010 1:26:26 PM |

    I'm with Jenny about the insulin thing. If we only know BG numbers, we still don't know whether it's because there's more carbs in einkorn or if it digests more slowly or something else. We must know how much insulin it takes to bring BG to those numbers.

    Incidentally, ketosis (and therefore AGE production and clearing) is also a function of how much insulin is flowing, not a function of how much blood glucose there is. So I guess you'll have to measure insulin to know what's what.

  • David M Gordon

    6/14/2010 1:26:26 PM |

    No, I have yet to try coconut flour. In an odd moment of serendipity, I received a scanned copy of the cookbook concurrent with your post.

    Odd, because for some health reason I do not recall (not allergy, though) I had strayed away from coconut everything. But things change.

    So I will share the cookbook with my wife, and request, nicely, we try a recipe or two. We attempt to go wheat-free this week, so I will wait out this test before trying, and then report back.

    PS: I receive the results of my lab tests this afternoon. I sure hope the many changes I put into place several months ago on your suggestions changed my numbers for the better!

  • Emily

    6/14/2010 1:41:04 PM |

    coconut flour/fiber isn't truly low in carbs, it has 8 grams carbs/ 2 Tablespoon sized serving. 5 grams of that is fiber, which according to some carb-counters, isn't counted as a true carb.

    also coconut flour bread tastes absolutely nothing like wheat bread.  i dont think i could convince a wheat lover that coconut flour bread was the way to go.

  • k

    6/14/2010 1:55:59 PM |

    Reminds me of Dr. Bernstein, when testing his blood sugar after eating various brands of crackers. He did find one that did not spike blood sugar levels - GG Scandinavian Crispbread, made from unprocessed wheat bran. I tried them and liken it to eating a wood shingle (ok, I imagine that is exactly what a wood shingle would taste like). He tries substituting it as bread in a couple of recipes. This struck me as almost sad; our craving and addiction to starch/sugar is mind blowing.

  • LeenaS

    6/14/2010 5:52:49 PM |

    Dear Dr Davis,

    Since you are experimenting, would you consider the option of making your own regular wheat bread the way you made the eikorn bread?

    Ready-milled whole wheat flour bought from a store differs dramaticlly from freshly milled flour, both enzymatically and in fatty acid quality. Only with freshly milled flour one has a chance to digest non-degraded Pufas (present in all grains).

    Regards,
    LeenaS

  • jandro

    6/14/2010 6:03:48 PM |

    Very interesting. I wonder if they both had the same caloric density. If eikorn has lower calories it would show a lower glucose response. I wonder what your reaction to something like a sweet potato is. I stay away from grains as they don't agree will with me.

    About coconut flour, I have used it before for making pancakes. I really like it but I LOVE coconut in general, someone who doesn't like coconut might feel differently about it. An advantage to other nut flours is that it's low in O6.

  • Tony

    6/14/2010 6:37:42 PM |

    The Many Uses of Coconut Flour:

    http://www.marksdailyapple.com/coconut-flour/

  • Marnae

    6/14/2010 8:04:58 PM |

    Yeast needs sugar to work properly--just a little sugar or honey would have made the bread rise much better. No sense using yeast if there's no sugar for it to eat.

  • DogwoodTree05

    6/14/2010 10:20:24 PM |

    Coconut flour is okay for brownies, bar cookies, and pancakes.  It would never yield an edible bread.  Gluten-free baked goods are unsatisfactory, IMO.  They have a somewhat crumbly texture, not spongy like wheat.  I have tried coconut, almond, and other gluten-free flours, including grain-based ones sold commercially.  Nothing can replace the spongy texture that wheat gives baked goods.  Save for the occasional bar cookie or pancake made with coconut or almond flour, I've given up eating flour-based products.

  • Michael

    6/14/2010 10:31:18 PM |

    Coconut flour is okay for some recipes but functionally speaking it certainly is not a substitute for sandwich bread.

    While it is not a grain I still had a weird feeling after eating it. I think it shares the same need as all flour to be fresh milled and used immediately, or fresh milled and then soaked or fermented in some way.

  • Dr. William Davis

    6/15/2010 2:10:09 AM |

    Hi, Leena--

    Actually, the whole wheat (not einkorn) bread was made from flour that was freshly ground. I shudder to think what might have happened had it been store-bought flour.

  • Cheryl

    6/15/2010 2:53:50 AM |

    Dr. Davis,

    I wonder if you'll try this experiment again, this time with a CGM and periodic draws to find out what your insulin level was.

    This experiment, to a more casual reader, provides too much hope (to a person with diabetes) that they can eat bread and still have optimal glucose levels.

    Diabetes has been documented in the ancient world it may be that a 'treat' wouldn't harm someone once, but a regular and consistent 'treat' becomes a habit. Poor habits are what precipitate diseases like Type 2 diabetes, yes?

  • Hans Keer

    6/15/2010 5:40:33 AM |

    Funny experiment, but as stated by other commenters, it does not say much. And as you have said before yourself: "The best thing is to avoid grain consumption". Some dangers of grains: http://bit.ly/ckgK4E

  • Alfredo E.

    6/15/2010 4:56:40 PM |

    Dr. Davis, you wrote: “After the conventional wheat, I also felt weird: a little queasy, some acid in the back of my throat, a little spacey. I biked for an hour solid to reduce my blood sugar back to its starting level”

    I am very interested to know how biking reduced your blood sugar after one hour. Do you have some ideas as how exercise can actually reduce blood sugar?

    In my case, I am pre diabetic and after one hour of intense exercise my blood sugar is very similar to before exercise, above 100's. Nevertheless, after some meals, it could come down to 80’s, how could that be explained?

    Best wishes,
    Alfredo E.

  • shutchings

    6/17/2010 7:21:21 AM |

    Where can you buy bread made from freshly ground wheat?!

  • rmarie

    6/17/2010 7:18:18 PM |

    @Alfredo
    I'm prediabetic too and I've discovered a quick and convenient way to lower my BG: I do 50-60 jumping jacks and if it's very high I'll add 20 pushups. It takes about 5 minutes and lowers my BG anywhere from 20 to 40 points in half an hour or so.

    The glucose in your body is reduced quickly because anaerobic exercise like that requires a lot of energy and it takes that in the form of glucose. So it's not an artifical lowering of BG like through medication. The body just uses up available glucose more quickly.

    Some may worry that such a large BG drop might make them hypoglycemic but I have never had that happen to me even before I was doing this. I'm not on any medication.

    Maybe Dr. Davis can elaborate on this a little more. We don't always have time or circumstance to go bike riding to lower our BG and for me this is a convenient alternative.

  • Carrie

    6/23/2010 12:03:26 AM |

    Dr. Davis-
    A friend of mine who is new to GF eating mentioned that her husband's blood pressure has stabilized rather quickly after eliminating wheat. I googled "GF for heart health", and was delighted to discover your blog.    

    My family eats grain free, and the only flour I use is coconut flour.  I recommend Bruce Fife's book "Cooking with Coconut Flour" as a jumping off point, because it explains how the properties of coconut flour make it unique to cook and bake with.  You NEED many more eggs than in a traditional bread recipe because that is what gives it a light airy texture, and you also need lots of fats to ensure it is moist.  I really don't do any cakes, cookies, etc because we try and stay low-carb, but the coconut flour has been great for breakfast, because neither my baby or I can eat eggs plain (wish I could, but they make me gag, he does too).  

    Coconut Flour Crepes:
    Mix
    2 eggs
    2 TBSP melted butter or coconut oil (if you use coconut oil, the eggs need to be room temp or it will clump up)
    Add 2 TBSP of sifted coconut flour and mix again until smooth.  
    Finally thin the mixture with about 1/3 cup of water and/or coconut milk
    (I use frozen from Asian market, not canned, and dilute it 50/50 with water and a drop of vanilla Stevia)

    cook crepes in pan brushed with ample coconut oil.  They are great with just butter.

  • David M Gordon

    6/23/2010 2:24:17 AM |

    Dr Davis,

    The book Carrie mentions, Cooking with Coconut Flour, is the one I mentioned last week. I have the entire book as a 2Mb pdf file, and am happy to share with anyone interested.

  • Kris

    6/28/2010 9:43:44 AM |

    Doctor Davis

    i think we are missing a very vital step here that is of fermenting wheat dough (making sourdough wheat). That is THE traditional style of consuming wheat everyday around the world.

    The process is neatly captured under subheading Europe:Sourdough Bread.

    http://wholehealthsource.blogspot.com/search/label/gluten


    That is how entire Indian subcontinent consumes wheat. That is approximately 2 billion people, not counting europe!

    I will really look forward to seeing how sourdough wheat plays out in these tests as that is the staple food for the vast majority day in and day out.

  • Ginger

    8/1/2010 8:09:31 PM |

    Great interview with einkorn wheat producer Etienne Mabille that may interest some of you: http://www.satoriz.fr/les-entretiens/Le-Petit-Epeautre-de-Haute-Provence/article-sat-info-500-5.html (you will have to use an online translation tool if you don't read french)

  • Chris Masterjohn

    9/16/2010 2:42:21 AM |

    Hi Dr. Davis,

    Interesting post.  I just received my shipment of einkorn today.  I'll be performing a more sophisticated version of your experiment on myself beginning next week and I'll let you know the results.  Just have to get a blood sugar-o-meter first.

    Chris

  • susan

    8/29/2012 4:32:22 PM |

    David M Gordon,
    is it still possible to get a copy of the coconut flour book?
    sue

  • Mark Richardson

    5/6/2014 4:19:47 PM |

    Tested my wife's BG before she ate a bowl of glutten free cereal 90. 1 hour latter was 308. I sure got her attention!

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Light the fuse of heart disease

Light the fuse of heart disease

Father Bob, despite his calling as a priest and counselor, led a stressful life. His average day was packed tightly with commitments: counseling members of his congregation, visiting the hospital, more official priest and church duties.

At age 53, his heart scan score of 799 came as a complete surprise. Even more of a surprise, his stress test was dramatically abnormal showing poor flow in the front of his heart at a level of exercise that wouldn't challenge most 75 year olds. His blood pressure with exericse: 230/100. Bob was shocked.

A few stents to the LDL later, Bob was trying to turn a new leaf on lifestyle. His life prior to the diagnosis of heart disease was driven by convenience. Because his day was so filled with commitments, he simply grabbed what he could from hospital cafeterias, fast foods, etc.

But after his procedure, Bob committed to choosing healthier foods, walk every day, and resist the food temptations presented by convenience.

However, temptation defeated him twice in the first few weeks after his stents. On the first occasion, Bob gave into eating a cheeseburger. On the second, Bob was at a fish fry (this is Wisconsin, after all) and ate a large serving of deep-fried fish.

On both occasions, Bob started feeling awful within minutes after eating: foggy, bloated, gassy, and fatigued. He took his blood pressure after each incident: 210/90, even though his blood pressure had more recently been trending down towards 130/80.

What happened? Grotesquely unhealthy foods like the deep-fried fish and cheeseburger provoke an abnormal constrictive process body wide. Some call this "endothelial dysfunction". Regardless, it is a graphic and frightening demonstration of the power of these sorts of unhealthy foods to wreak immediate and dangerous effects. Father Bob's response was more exagerrated than most, but it happens to all of us.

Eat badly and your body will pay the price. Even that occasional hot chocolate sundae or Egg McMuffin will yield cumulative injury, among which will be a rise in your heart scan score.

Comments (1) -

  • madcook

    10/27/2006 4:22:00 AM |

    Okay, I'm feeling sufficiently guilty just reading this.  Yes, I know intellectually about postprandial lipid surges and such... but given that in the real world sometimes we are caught in situations where there isn't a lot of healthy foods available:  By way of instruction, how could the Good Father have salvaged these situations from disaster?  What choices could he have made in these situations which would have been better, healthier (yes, I know about the lunch pail and packing good, healthy foods to take from home, and do it all the time).  But WHAT IF he didn't have the option of bringing his own food to a restaurant or social "fish fry" situation?  What to do then, constructively, besides a heavy dose of guilt?

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Rerun: To let low-carb right, you must check POSTPRANDIAL blood sugars

Rerun: To let low-carb right, you must check POSTPRANDIAL blood sugars

Checking postprandial (after-eating) blood sugars yields extraordinary advantage in creating better diets for many people.

This idea has proven so powerful that I am running a previous Heart Scan Blog post on this practice to bring any newcomers up-to-date on this powerful way to improve diet, lose weight, reduce small LDL, reduce triglycerides, and reduce blood pressure.



To get low-carb right, you need to check blood sugars

Reducing your carbohydrate exposure, particularly to wheat, cornstarch, and sucrose (table sugar), helps with weight loss; reduction of triglycerides, small LDL, and c-reactive protein; increases HDL; reduces blood pressure. There should be no remaining doubt on these effects.

However, I am going to propose that you cannot truly get your low-carb diet right without checking blood sugars. Let me explain.

Carbohydrates are the dominant driver of blood sugar (glucose) after eating. But it's clear that we also obtain some wonderfully healthy nutrients from carbohydrate sources: Think anthocyanins from blueberries and pomegranates, vitamin C from citrus, and soluble fiber from beans. There are many good things in carbohydrate foods.

How do we weigh the need to reduce carbohydrates with their benefits?

Blood sugar after eating ("postprandial") is the best index of carbohydrate metabolism we have (not fasting blood sugar). It also provides an indirect gauge of small LDL. Checking your blood sugar (glucose) has become an easy and relatively inexpensive tool that just about anybody can incorporate into health habits. More often than not, it can also provide you with some unexpected insights about your response to diet.

If you’re not a diabetic, why bother checking blood sugar? New studies have documented the increased likelihood of cardiovascular events with increased postprandial blood sugars well below the ranges regarded as diabetic. A blood sugar level of 140 mg/dl after a meal carries 30-60% increased (relative) risk for heart attack and other events. The increase in risk begins at even lower levels, perhaps 110 mg/dl or lower after-eating.

We use a one-hour after eating blood sugar to gauge the effects of a meal. If, for instance, your dinner of baked chicken, asparagus brushed with olive oil, sauteed mushrooms, mashed potatoes, and a piece of Italian bread yields a one-hour blood sugar of 155 mg/dl, you know that something is wrong. (This is far more common than most people think.)

Doing this myself, I have been shocked at the times I've had an unexpectedly high blood sugar from seemingly "safe' foods, or when a store- or restaurant-bought meal had some concealed source of sugar or carbohydrate. (I recently had a restaurant meal of a turkey burger with cheese, mixed salad with balsamic vinegar dressing, along with a few bites of my wife's veggie omelet. Blood sugar one hour later: 127 mg/dl. I believe sugar added to the salad dressing was the culprit.)

You can now purchase your own blood glucose monitor at stores like Walmart and Walgreens for $10-20. You will also need to purchase the fingerstick lancets and test strips; the test strips are the most costly part of the picture, usually running $0.50 to $1.00 per test strip. But since people without diabetes check their blood sugar only occasionally, the cost of the test strips is, over time, modest. I've had several devices over the years, but my current favorite for ease-of-use is the LifeScan OneTouch UltraMini that cost me $18.99 at Walgreens.

Checking after-meal blood sugars is, in my view, a powerful means of managing diet when reducing carbohydrate exposure is your goal. It provides immediate feedback on the carbohydrate aspect of your diet, allowing you to adjust and tweak carbohydrate intake to your individual metabolism.

Comments (12) -

  • Chris Keller

    4/1/2010 9:56:58 PM |

    I understand low carb diets in general, but the way you talk about postprandial blood sugar levels, what can you eat?  

    You continuously point out that foods you didn't think would cause high blood sugars do (is it because of the actual food or hidden ingredients like sugar), so what's on your acceptable list?  (in general).  I realize everyone's body will react slightly differently...

  • kris

    4/2/2010 2:41:20 AM |

    Dr. davis,
    I always follow your valuable blogs. please keep up the good work. here is the link to the type of meals to cut down on the carbs.checkk it out.
    http://www.phlaunt.com/diabetes/18856280.php

  • Anonymous

    4/2/2010 8:29:25 AM |

    My suspicion is that the balsamic vinegar was the culprit. Some brands are extremely sweet because they have added sugar.

  • Anonymous

    4/2/2010 12:54:14 PM |

    Dr. Davis,
    What is an acceptable blood glucose level after a meal? What goal do you recommend for your patients?

  • DrStrange

    4/2/2010 4:55:55 PM |

    I don't know about the Life Scan bg monitor but I do know that some monitors are totally inadequate!  Walmart Relion for one.  I have one and can easily do 2 tests within a few seconds of each other and get readings of 180 and 135!!!!  AcuCheck by Aviva which I also have has never given me a multiple reading spread of more that about 5 points, and that is a 3 year old meter.  You don't do yourself any favors by going cheap. It you have a sympathetic doc who will write a scrip you can get meter for free and have a big chunk of test strip cost covered.

  • Michael Barker

    4/2/2010 9:17:23 PM |

    You should add this one caveat. Fructose and its various aliases does not raise blood sugar immediately. It will do so eventually when it screws up your liver.

    Mike

  • Narda

    4/3/2010 2:33:53 PM |

    Regarding the dressing...I learned decades ago in high school biology that vinegar turns to sugar in the blood. Is this true?

  • TedHutchinson

    4/3/2010 4:11:09 PM |

    Regulars will know I bought a meter after the first appearance of this post. I was regularly over 8.6 = 155 at one hour.
    Went to doctor fasting blood glucose 4.9= 88.2 and HbA1c 5.6 = 100.8 which my doctor thought fine.
    I pointed out the day before and day after my meter was reported much higher numbers, he suggested a fasting oral glucose tolerance test for which I had to prepare by consuming 175mg carbs daily for 3 days, which I did gaining several lbs.
    However 2hr reading 5.8 = 105
    My meter reported  11.3 =203.4 at 1 hr but I peaked at 17.3 = 311.4 the following meal.
    Inflammation markers and metabolic characteristics of subjects with one-hour plasma glucose levels
    this paper suggests that Elevated one hour plasma glucose (1hPG) in people with normal glucose tolerance and pre-DM subjects is associated to subclinical inflammation, high lipid ratios and insulin resistance. Therefore, 1hPG >155 ( = 8.6) could be considered a new 'marker' for cardiovascular risk.
    Medscape article on same paper.
    One-Hour Plasma Glucose Levels May Be a Marker for Cardiovascular Risk

    So as far as my doctor is concerned I've no problems whatsoever. It seems to me absurd that if I followed his advice I'd be a diabetic basket case and the situation would be almost irretrievable before they will take any action.
    I've been a bit stricter with the carbs and have followed some other suggestions so have managed to keep 1hr numbers below 6.7 = 120

  • Anonymous

    4/6/2010 1:54:16 PM |

    So if the peak blood glucose is important, then things that lower it are generally good? Foods with a low glycemic index, which are slow release?  Polyphenols like green tea and red wine, which inhibit amylase and reduce the sugar spike?

  • Anonymous

    4/8/2010 11:21:34 AM |

    You have a choice?

    To die of heart disease or alzheimers?

    http://www.naturalnews.com/028523_Alzheimers_juicing.html

    "Those who drank juice three or more times per week experienced a 76 percent reduced risk for Alzheimer's. Those who drank juice once or twice a week experienced a 16 percent reduced risk."

    But various polyphenols have been show to also modify glucose levels in some cases?

  • jpatti

    5/7/2010 7:46:47 AM |

    What you can eat is *based* on postprandial bg.  

    My husband can eat 1/6th of a 2-layer chocolate cake.  

    I can eat around 20g carb at breakfast, 40g at lunch and dinner, and that requires insulin injections.

    We're all different, you have to test yourself: http://www.alt-support-diabetes.org/new.php

  • Anonymous

    4/20/2011 12:08:55 PM |

    After finding your blog, I purchased a blood glucose monitor and have been checking my post-prandial blood sugars 1 and 2 hours after eating a meal.  I am also checking some fasting a.m. blood sugars.

    I am obese, though I have lost 49 pounds by reducing overall carb intake and eliminating all grains, sugars and processed foods.  I eat primarily a whole food diet other than a little (.25 oz.) of very dark chocolate a day (85%).

    My post-prandial 1 hour are between 90-110 most meals, and 2 hours are almost always below 100.  However, I am noticing that my fasting blood sugars are rising, sometimes above 100.

    Should I be concerned?  Is there anything I can be doing differently to reduce the insulin resistance that seems to be developing due to carb restriction?  Total carb intake daily is around 50 grams, including fiber.

    Stephanie A.

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Tim Russert's heart scan score 210. . .in 1998

Tim Russert's heart scan score 210. . .in 1998

Despite the media blathering over how Mr. Russert's tragic death from heart attack could not have been predicted, it turns out that he had undergone a heart scan several years ago.

A New York Times article, A Search for Answers in Russert’s Death, reported:

Given the great strides that have been made in preventing and treating heart disease, what explains Tim Russert’s sudden death last week at 58 from a heart attack?

The answer, at least in part, is that although doctors knew that Mr. Russert, the longtime moderator of “Meet the Press” on NBC, had coronary artery disease and were treating him for it, they did not realize how severe the disease was because he did not have chest pain or other telltale symptoms that would have justified the kind of invasive tests needed to make a definitive diagnosis. In that sense, his case was sadly typical: more than 50 percent of all men who die of coronary heart disease have no previous symptoms, the American Heart Association says.

It is not clear whether Mr. Russert’s death could have been prevented. He was doing nearly all he could to lower his risk. He took blood pressure pills and a statin drug to control his cholesterol, he worked out every day on an exercise bike, and he was trying to lose weight, his doctors said on Monday. And still it was not enough.

“What is surprising,” Dr. Newman said, “is that the severity of the anatomical findings would not be predicted from his clinical situation, the absence of symptoms and his performing at a very high level of exercise.”


Buried deeper in this article, the fact that Mr. Russert had a heart scan score of 210 in 1998 is revealed.

That bit of information is damning. Readers of The Heart Scan Blog know that heart scan scores are expected to grow at a rate of 30% per year. This would put Mr. Russert's heart scan score at 2895 in 2008. But the two doctors providing care for Mr. Russert were advising the conventional treatments: prescribing cholesterol drugs, blood pressure medication, managing blood sugar, and doing periodic stress tests.

Conventional efforts usually slow the progression of heart scan scores to 14-24% per year. Let's assume the rate of increase was only 14% per year. That would put Mr. Russert's 2008 score at 779.

A simple calculation from known information in 1998 clearly, obviously, and inarguably predicted his death. Recall that heart scan scores of 1000 or greater are associated with annual--ANNUAL--risk for heart attack and death of 20-25% if no preventive action is taken. The meager prevention efforts taken by Mr. Russert's doctors did indeed reduce risk modestly, but it did not eliminate risk.

We know that growing plaque is active plaque. Active plaque means rupture-prone plaque. Rupture prone plaque means continuing risk for heart attack and death. Heart attack and death means the approach used in Mr. Russert was a miserable failure.

While the press blathers on about how heart disease is a tragedy, as Mr. Russert's doctors squirm under the fear of criticism, the answers have been right here all alone. It sometimes takes a reminder like Mr. Russert's tragic passing to remind us that tracking plaque is a enormously useful, potentially lifesaving approach to coronary heart disease.

Who needs to go next? Matt Lauer, Oprah, Jay Leno, some other media personality? Someone close to you? Can this all happen right beneath the nose of your doctor, even your cardiologist?

I don't need to remind readers of The Heart Scan Blog that heart disease is 1) measurable, 2) trackable, 3) predictable. Mr. Russert's future was clear as long ago as 1998. Every year that passed, his future became clearer and clearer, yet his doctors fumbled miserably.



Copyright 2008 William Davis, MD

Comments (10) -

  • Richard A.

    6/18/2008 4:51:00 AM |

    "He also had a dangerous combination of other risk factors: high triglycerides, a type of fat in the blood, and a low level of HDL, the “good cholesterol” that can help the body get rid of the bad cholesterol that can damage arteries."

    I wonder if he was taking fish oil supplements to try to drive down his triglycerides and niacin to prop up his HDL?

  • Anonymous

    6/18/2008 5:36:00 AM |

    I had a 234 score in 2005 and a 419 score in 2007 - if it wasn't for resources like TYP - I wouldn't have pushed my Dr with questions about Vit D and CQ 10 and Fish Oil...  sit waiting for the next scan to see if things are under control (now - small LDL-P 123 nmol/L).

    Just think if Tim R had the time to do a bit of research himself and found TYP - but that is what your physicans should be doing for you.... growing... learning... but as an engineer, I know the spectrum of people calling themselves engineers is a large spectrum... so it is with MDs.

    Thanks for what you do Dr D.

    Dave

  • Dr. William Davis

    6/18/2008 11:53:00 AM |

    Yes. Fish oil alone could have cut his risk of sudden cardiac death by 45%. It would have cost him all of $3 per month.

  • Anonymous

    6/18/2008 3:09:00 PM |

    I have been wondering if the trans-Atlantic flight several days before his death could have had something to do with it...

  • Anonymous

    6/18/2008 5:08:00 PM |

    Dr Davis I just wonder what you think of this Dr. Mehmet(?) Oz who keeps popoing up on television and writing books talking about the same old stuff, low fat, high carbs blah blah blah . . . I think since Mr. Russerts death I've seen him on tv 3 times and NOT ONCE has he mentioned calcium scoring, vitamin D, fish oil . . .

  • Anonymous

    6/19/2008 3:45:00 AM |

    What a tragedy.  All week long I have been asking myself how such a smart man could be so uninformed about his own health?

    With all the resources at Mr. Russert's disposal, I would think he could have easily learned more about his condition, and the measures he might have taken to save himself.  [Then too, he might have also come across the Track Your Plaque website... or the book.]  Instead, he was apparently greatly trusting of his internist and cardiologist, and perhaps thought he was receiving optimal medical management... and nothing more could be done?

    Beyond that, I wonder about his Vitamin D status, and whether he was dehydrated from the long flight back from Europe?  I also wonder if the emotional stresses (good and bad) of a quick trip to Europe, his son's graduation from college, and having recently placed his beloved father into a care home, on top of what could only be termed a stressful and grueling work life (no matter how much he may have loved it) might have lead his body to the tipping point on that day.   I suppose we are unlikely to have these answers under the circumstances.

    R.I.P. Mr. Russert, but shame, shame, shame on your physicians, IMO they really let you down.

    Thanks for this truthful blog, an antidote to all the media nonsense and C.Y.A. I have seen in the past few days.

    Terri
    madcook

  • sschein

    6/23/2008 5:36:00 PM |

    My wife has been to Dr. Michael Newman the internist for Tim Russert.  I don't think she is going back.  I had Angioplasty about 10 years ago with stents put in my right and left artery.  Since then I have the thallium stress test every year, take 1500 mg's of niaspan a day, Lipitor, a blood pressure lowering drug, and aspirin.  Both my cardiologist, and my internist state that a heart scan would not do me any good, and my cardiologist stated that the heart scan would simply confuse the issues.  Are they right? Would the heart scan harm me?  If so, how?

  • Anonymous

    6/25/2008 5:18:00 PM |

    In response to the comment by sschein, I'm not sure it's such a great idea to have a thallium stress test every year.  You should probably investigate the possibility of a CT-angiogram.  

    I am not a doctor so I don't want you to think I'm defending them, but there's only so much that a doctor can do in the office visit environment.  It's really up to the patient to do the research and decide on what he believes is the best course of treatment for him or herself and then try to bring the doctor around to his point.  In my own case I refuse to have a thallium stress test and have finally decided to have a 320 slice CT-angiogram when I go to Boston next month.  My cardiologist may not agree that it's the choice he'd choose, but he's going along with it.  Quite simply they don't have the time to convince the patient one way or the other.  We really don't know all the details about Tim Russert's care.  If he had his own private physician who tended only to him or who was consulted extensively I'd probably expect better.  As just one patient (admittedly a famous one) I'm not sure how much you can expect from a doctor.  If he suggests a stress test or an angiogram and you think better of the idea, it's up to the patient to chart his own course.

    Andy (the164club) TYP member

  • Jeffrey Dach MD

    7/1/2008 11:38:00 AM |

    Tim Russert and George Carlin

    Two beloved American celebrities have succumbed to heart disease before their time.  The national response has been disappointment in a medical system that could allow this to happen.  What could have been done differently to save the lives of both Tim and George, to avoid this fatal outcome?

    To read more...Saving Tim Russert and George Carlin by Jeffrey Dach MD


    Jeffrey Dach MD
    4700 Sheridan Suite T
    Hollywood FL 33021
    my web site

  • buy jeans

    11/3/2010 6:54:38 PM |

    A simple calculation from known information in 1998 clearly, obviously, and inarguably predicted his death. Recall that heart scan scores of 1000 or greater are associated with annual--ANNUAL--risk for heart attack and death of 20-25% if no preventive action is taken. The meager prevention efforts taken by Mr. Russert's doctors did indeed reduce risk modestly, but it did not eliminate risk.

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