I don't care about hard plaque!

I ran into a cardiology colleague this weekend. He was aware of my interest in CT heart scanning and plaque reversal.

Out of the blue, he declared "I don't care about hard plaque! I only care about soft plaque." He then proceeded to describe to me how everyone--EVERYONE--needs a CT coronary angiogram to identify "soft plaque".

Is there any truth to this view? Are we only identifying "hard plaques" by focusing on calcium and calcium scores on simple CT heart scans?

Several issues deserve clarification. First of all, CT heart scans don't identify hard plaque. They identify total plaque. Because calcium is a component of the majority of atherosclerotic plaque, comprising approximately 20% of its volume, a calcium "score" can be used to indirectly quantify total plaque, both "hard" and "soft".

Anyone cardiologist who performs a lot of the procedure, intracoronary ultrasound, knows that most human plaque is also not purely soft or hard, it is mixture of both. (I've been performing this procedure since 1995.) Quantifying only soft or only hard plaque is therefore only possible in theory, not in practice.

I believe my colleague does have a valid point in one regard, however. There is indeed a small percentage of people, probably around 5% of all people who have CT heart scans, who have scores of zero yet have a modest quantity of pure "soft" plaque. These people may be misled by having a zero score. How can these people benefit from better information?

Several ways. First, people like this tend to have very high LDL cholesterols, generally 180 mg/dl or greater. They may have a very worrisome family history, e.g., father with heart attack in his 30s or 40s. This small proportion of people with zero heart scan scores may benefit from receiving X-ray dye with their heart scan, i.e., a CT coronary angiogram. Keep in mind that we're assuming everyone is without symptoms, also. If symptoms are part of the picture, everything changes.

But should everybody get a CT coronary angiogram? I don't believe so. A CT coronary angiogram involves far more radiation exposure, greater expense (usually $1800 to $4000), and, with present day technology, does not yield quantitative (measurable) information that is useful for longitudinal use for repeated scans. You don't want to undergo yearly CT coronary angiograms, for instance.

Stay tuned for more on this issue. In the meantime, I continue to try and inform my colleagues about what is right, what is wrong, what is preferable for patient safety and yields truly empowering information, and try to impress on them that the practice of cardiology is not just about enriching their retirement accounts.

Comments (10) -

  • Dave K

    11/18/2007 3:48:00 PM |

    Hello Dr Davis,

    Interesting post about hard and soft plaque.  I recently had a discussion with my GP regarding my serious increase in scan score (Jan 2006 = 235, Nov 2007 = 419).  

    After the first scan we started aggressively going after my LDL, HDL and Trig.. 196,59,221

    And have them down to 103, 65, 92 - we still have a way to go to 60/60/60 -

    So the increase is a suprise, but my doctor said that the increase could in part be cause some of the soft plaque had been converted to hard plaque and the scan would show that conversion.

    Does hard plaque register more than soft?

    Thanks for what you  are doing.

  • Dr. Davis

    11/18/2007 4:12:00 PM |

    Hi, Dave--

    I'm glad your doctor is working with you on gaining better control over your plaque growth.

    However, there is no such thing as soft plaque converting to hard plaque to increase calcium scores.

    Think of it this way: Calcium is a surrogate measure of TOTAL plaque, both soft and hard. In the majority of settings, there is little advantage to characterizing soft vs. hard.

    To seize better control, don't neglect: 1) hidden lipoprotein patterns, 2) vitamin D. Also see  our report "10 steps to take if your heart scan score increases more than 10% per year" at http://trackyourplaque.com/library/fl_02-006tensteps-2.asp.

    Good luck!

  • Dave K

    11/19/2007 4:50:00 PM |

    Dr Davis,

    Thanks for the response.

      I wonder if you are seeing any trends that indicate a "flywheel" or momentum in the creation of plaque.  I notice you have some patients that take two years or more to stop the growth.  

    Starting point Jan 06 - score=236
    Quit smoking - Jan 06
    Vitamin D - taking 1200
    Lost 20 #'s (5'11)=195
    Exercise 40min 4x
    Fish Oil = 1600 DHA+EHA
    Crestor = 10mg
    baby aspirin
    Basic good diet - no processed foods
    Oatmeal and blueberries/raisins everyday.

    This month = score=419

    After last scan
    just added Zetia
    Just quit all wheat products
    Considering quiting redwine - I tend to have 3-4 glasses versus the recommended 2
    Doctor is still saying no to L-arginine (not enough studies)
    Considering Niaspan

    Any comments?

    Thanks again - Dave K

    P.S. One more question... maybe this should be a separate post.  Do we know the exact connection between smoking and plaque?  Does it lower LDL size, lower HDL - iritate the lining of the vessels? Is it just elevated blood pressure?  What did my thirty years of smoking do to my heart (versus lungs)?

  • Dr. Davis

    11/19/2007 11:48:00 PM |

    Hi, Dave--

    I'm afraid there's too much to cover in this Blog. You will need lipoprotein testing and almost certainly require more than a baby-dose of vitamin D to gain better control over plaque growth. This rate of growth, however, is very concerning.  

    I would invite you to look at the hundreds of pages of discussion on the www.trackyourplaque.com website devote to just this question.

  • Anonymous

    11/20/2007 3:13:00 AM |

    Thanks Again Dr Davis,

    I have poured over your website and I'm still reading.  I plan to make your list of turn around "stars".

    BTW - here is the comment from my GP - sounds exactly like the cardiologist you mentioned in the original post.

    "Remember that although your coronary calcium score has gone up, this does not mean that you are at greater risk than you were a year ago.  Remember that the most dangerous plaque is the not-yet calcified soft plaque, which will not show up on an EBT.  It is only the safe, calcified plaque that can be measured with the EBT.   For your score to go up like it did, while your lipids came down so much, what had to happen was that lots of dangerous unstable plaque was converted to stable, calcified plaque.    There are no accepted guidelines for interpreting changes in calcium scores over time, because the scores tend to go up as treatment converts dangerous plaque to safer plaque.    We do know that aggressively lowering LDL reduces both unstable and stable plaque, and we know that risk can be further lowered by adjuvant therapy such as I listed above. "

  • Dr. Davis

    11/20/2007 3:44:00 AM |

    Sigh . . .

    It's amazing what a simple reading of the literature by your doctor would reveal to him/her.

    In near future, I will be posting some blogs that summarize crucial studies in the heart scan literature in an effort to provide better weapons in your fight.

  • Dave K

    11/20/2007 5:53:00 AM |

    Dr Davis,

    Thanks again for all you are doing and I look forward to whatever you can post.  I plan to challenge some of my GPs positions.  Your data certainly is of enormous value.

    Dave K

  • Dave K

    11/20/2007 5:57:00 AM |

    P.S. I going to 2000 vit "D" tomorrow.

    Also - have you thought about a "track-your-plaque" certification.  Something to indicate that our Drs are at least up to speed on the latest in *preventative* proceedures...?  I would switch.....

  • Dr. Davis

    11/20/2007 11:49:00 AM |

    Hi, Dave--

    Yes, excellent thought.

    It is something we'd like to aim for, but over the long term, since right now there are too few to make a difference. One by one, they are declaring themselves and separating from the "pack."

  • buy jeans

    11/3/2010 8:48:59 PM |

    Stay tuned for more on this issue. In the meantime, I continue to try and inform my colleagues about what is right, what is wrong, what is preferable for patient safety and yields truly empowering information, and try to impress on them that the practice of cardiology is not just about enriching their retirement accounts.

Loading
Fanatic Cook on the American Heart Association

Fanatic Cook on the American Heart Association

The Fanatic Cook has posted a stinging criticism of the American Heart Association (AHA):

American Heart Association My Fat Translator

Beyond the nonsensical nutritional recommendations (e.g., substitute small French fries for large French fries), she lists the major financial contributors to the AHA, a Who's Who in the pharmaceutical and processed food industry.


"For an organization that brought in close to a billion dollars last year, you'd think they could come up with something a little more pronounced. If I was more cynical I'd say the AHA had an interest in keeping Americans fat . . . or at least dependent on a highly-processed, fast food diet, requiring drugs to tweak lab values."

To be sure, the AHA does a great deal of good in funding research and educating the public about the prevalence of heart and vascular disease. But their fund raising interests have clearly subverted the honesty of their nutritional advice. Sadly, it is the AHA dietary advice that hospital dietitians use in counseling people with heart disease after their heart attack, stent, or bypass surgery. After my patients are discharged from the hospital for any reason, I tell them to please forget everything the nice hospital dietitian told them. It is not okay to eat the factory farm-raised hamburger on the sugar-equivalent enriched flour bun. Low-fat ice cream is not a healthy substitute for full-fat ice cream.

The AHA is no different than the USDA and the American Diabetes Association, "official" organizations that have, in effect, sold out to industry.

Comments (7) -

  • Anonymous

    6/8/2008 9:34:00 PM |

    There is a show that I watch from time to time called Man vs Wild.  It is OK entertainment, and most importantly, my nephews enjoy the show.  It gives us something to talk about.  If you haven't seen it, the program is about a former British military specialist named Bear that goes out into different wild locations to show how to survive.  He eats gushy bugs and wild vegetables for food, builds forts to sleep in, etc.  

    I happened to stumble onto an article about Bear a # of months ago.  It said that he has a condition that predisposes him to have high cholesterol.  His father died from a heart attack so as of last year he says he is now eating an all vegetable, whole grain, starchy, diet when at home.  He also mentions his new diet on his web sight in which he quotes from the World Health Organization for what that organization believes to be proper food to eat to be healthy.  http://www.beargrylls.com/health.html    

    (I hope kids are not following his blog eating suggestions.)  

    I mention this because my nephews and I have noticed that it looks like Bear has grown a little tube around the belly for this newer season.  I think Bear would be better off eating the Paleo diet that he does in the Man vs Wild show than his starchy WHO approved diet.  I wrote him a message to that effect and mentioned if he wanted to prevent heart disease, there was no better place to learn from than the TYP web sight.      

    Talking about the good and the bad of corporations spreading the word about good nutrients, I heard a rumor that a larger German health food/ drug company is working on or coming out with a "unique" vitamin D.  I used to work in the health food industry several years ago and know the main researcher doing the work.  He seems like an honest guy.  When we worked together he was in charge of researching polycosanols.  The company had a patent on them and wanted to come out with a unique product.  I remember he tested the polys but he never found them to work at lowering cholesterol.  The company did not like the results, but he stuck with what he found and the company never did sell polycosanols. So when it comes to any new Ds hitting the market I doubt this company will be coming out with another no flush niacin.  It will be something that works is my guess, but will the newly marketed D be better than what is already about there......

    Off topic, had lunch with the owner of one of the larger independent health food testing labs in US last week.  He lives in the same town as I.  I told him that I was now taking D3 and he said he was receiving many many orders for testing this.  D3 testing is popular this year.  He then volunteered that many companies are now testing for vitamin K2-7 also.  Good to see your word along with others on the importance of these nutrients is getting out.

  • Anonymous

    6/9/2008 3:21:00 AM |

    We (my son & I) watched Man Vs. Wild just last night.  He ate raw yak liver, blood, & eyeballs in frigid Siberia, near the border of Mongolia, as well as blood sausage with the local people in their yurt.  His paleo nutrition is usually quite accurate.  I'm really surprised he fell for the WHO advice, since he sees how indigenous people often live quite well on traditional foods.  

    On the other hand, we prefer the Survivorman series, which has a similar premise, but less "sensational".  Unlike Man vs. Wild, Survivorman goes it alone, without a camera crew.  He has to carry his own gear (minimal for himself) and set up his own camera shots and footage.  Unlike Bear, he downplays the "ugh, look what I have to eat to survive" attitude.

  • Anonymous

    6/9/2008 1:39:00 PM |

    I am a dietitian that works with heart patients, and I do NOT recommend the AHA guidelines.  I actually have to spend a large amount of my time re-teaching them what their cardiologists and other health care professionals have been spouting off.  Just letting you know that not all dietitians are mindless AHA and ADA believers.

  • Dr. William Davis

    6/10/2008 12:13:00 PM |

    Dear dietitian--

    That's great!

    I am thrilled that you have the courage to speak out and express what you believe to be true, not what you're told to believe.

    Keep it up!

  • Ivan Road

    6/11/2008 5:29:00 PM |

    Except Fanatic Cook lives on wheat and grains.  Little disconnect there.

  • Dr. William Davis

    6/11/2008 5:36:00 PM |

    Hi, Ivan--

    Uh, oh. We should talk to her about that.

  • Anna

    6/13/2008 4:05:00 AM |

    Yeah, I dropped Fanatic Cook from my reading list some time ago.  Little new or useful to learn there after she went a bit overboard on the "whole grains are good thing".  She moved into vegetarianism and veganism as an attempt to prevent cancer, and for the most part, provides some really weak support for that position.  I could say more, but I think I'll leave it at that.

    Nice to hear she is seeing the AHA clearly, though.

Loading