Are we a front for drug companies?

I was shocked recently when someone accused me and the Track Your Plaque website of being nothing more than a front for the drug industry, that we are promoting concepts with the hidden pharmacuetical agenda behind us.

Don't make me laugh. How in the world that kind of impression could be gotten from either the Heart Scan Blog or the Track Your Plaque website is beyond me.

But I occasionally do need to state explicity: We do not promote drugs, neither this Blog nor the Track Your Plaque website has ever sought nor been backed by pharmaceutical money. The only money that supports this website is our own and that from paying Track Your Plaque members.

In fact, I am quite proud of the unbiased content and commentary on both venues. I challenge anyone to point out how and where there is any suggested relationship to a hidden source of commercial backing. I assure you, there is none.

If I say a drug is worth you and your doctor considering, then I say so with a true belief in it, not because somebody or some company paid me to say so. If I say a drug stinks, I believe that too. If we use a specific supplement in the program, it's because we believe it truly adds value to a plaque-reversal program. We receive no money from drug, supplement, or other commercial interests to promote their products. Period.

Comments (3) -

  • Anonymous

    5/1/2007 8:06:00 PM |

    You are so right, i cannot beleive that anyone would think that

  • Regina Wilshire

    5/2/2007 6:33:00 PM |

    It comes with the territory - chalk it up and keep writing!

  • Dr. Davis

    5/3/2007 12:41:00 AM |

    What bothers me is that, with so much health information in the world, it's becoming tougher and tougher to tell what's genuine and what's marketing, lies, or other just plain nonsense. But thanks for the encouragement.

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Food sources of vitamin K2

Food sources of vitamin K2



Vitamin K2 is emerging as an exciting player in the control and possible regression of coronary atherosclerotic plaque. Only about 10% of dietary vitamin K intake is in the K2 form, the other 90% being the more common K1.

The ideal source of K2 is natto, the unpalatable, gooey, slimy mass of fermented soybeans that Japanese eat and has been held responsible for substantial decreases in osteoporosis and bone fractures of aging. Natto has an ammonia-like bouquet, in addition to its phlegmy consistency that makes it virtually inedible to anyone but native Japanese.

I say that the conversation on vitamin K2 is emerging because of a number of uncertainties: What form of vitamin K2 is best (so-called MK-4 vs. MK7 vs. MK-9, all of which vary in structure and duration of action in human blood)? What dose is required for bone benefits vs. other benefits outside of bone health? Why would humans have developed a need for a nutrient that is created through fermentation with only small quantities in meats and other non-fermented foods?

Much of the developing research on vit K2 is coming from the laboratories of Drs. Vermeer, Geleijnse, and Schurgers at the University of Maastricht in the Netherlands, along with several laboratories in Japan, the champions of K2.

MK-7 and MK-8,9,10 come from bacterial fermentation, whether in natto, cheese, or in your intestinal tract; MK-4 is naturally synthesized by animals from vitamin K1. While natto is the richest source of the MK-7 form, egg yolks and fermented cheeses are the richest sources of the MK-4 form.

Chicken contains about 8 mcg MK-4 per 3 1/2 oz serving; beef contains about 1 mcg. Egg yolks contain 31 mcg MK-4 per 3 1/2 oz serving (app. 6 raw yolks). Hard cheeses contain about 5 mcg MK-4 per 3 1/2 oz serving, about 70 mcg of MK-8,9; soft cheeses contain about 30% less. Natto contains about 1000 mcg of MK-7, 84 mcg MK-8, and no MK-4 per 3 1/2 oz serving.











Feta cheese

Thanks to the research efforts of the Dutch and Japanese groups, several phenomena surrounding vitamin K2 are clear, even well-established fact:

--Vitamin K2 supplementation (via frequent natto consumption or pharmaceutical doses of K2) substantially improves bone health. While K2 by itself exerts significant bone density/strength increasing properties in dozens of studies, when combined with other bone health-promoting agents (e.g., vitamin D3, prescription drugs like Fosamax and calcitonin), an exaggerated synergy of bone health-promoting effects develop.



--The MK-4 form of vitamin K2 is short-lived, lasting only 3-4 hours in the body. The MK-7 form, in contrast, the form in natto, lasts several days. MK-7 and MK-8-10 are extremely well absorbed, virtually complete.

--Bone health benefits have been shown for both the MK-7 and MK-4 forms.

--Coumadin (warfarin) blocks all forms of vitamin K.





Interestingly, farm-raised meats and eggs do not differ from factory farm-raised foods in K2 content. (But please do not regard this as an endorsement of factory farm foods.)

Another interesting fact: Since mammals synthesize a small quantity of Vit K2 forms from vitamin K1, then eating lots of green vegetables should provide substrate for some quantity of K2 conversion. However, work by Schurgers et al have shown that K1 absorption is poor, no more than 10%, but increases significantly when vegetables are eaten in the presence of oils. (Thus arguing that oils are meant to be part of the human diet. Does your olive oil or oil-based salad dressing represent fulfillment of some subconscious biologic imperative?)

If we believe the data of the Rotterdam Heart Study, then a threshold of 32.7 micrograms of K2 from cheese yields the reduction in cardiovascular events and aortic calcification.

It's all very, very interesting. My prediction is that abnormal (pathologic) calcium deposition will prove to be a basic process that parallels atherosclerotic plaque growth, and that manipulation of phenomena that impact on calcium depostion also impact on atherosclerotic plaque growth. Vitamins D3 and K2 provide potential potent means of at least partially normalizing these processes.

As the data matures, I am going to enjoy my gouda, Emmenthaler, Gruyere, and feta cheeses, along with a few egg yolks. I'm going to be certain to include healthy oils like olive and canola with my vegetables.


All images courtesy Wikipedia.

Copyright 2007 William Davis, MD

Comments (46) -

  • MAC

    12/28/2007 5:58:00 PM |

    Is not magnesium also a regulator of calcium?

    NIH link on magnesium: http://www.ods.od.nih.gov/factsheets/magnesium.asp
    though they really don't spell out magnesium's role in regulating calcium, just that it "keeps bones strong".

    Dr. Eades blog on magnesium and it's deficiency and role in inflammation: http://www.proteinpower.com/drmike/uncategorized/magnesium-and-inflammation/

    BTW Dr. Davis, Dr. Eades recently posted a comment on your TYP book as the best source regarding CT heart scans.

  • Anonymous

    12/28/2007 7:05:00 PM |

    Fascinating! Perhaps K2 is one factor that contributes to the so-called French paradox. It might make sense to eat imported cheeses produced by traditional methods in European countries that have the lowest rates of CHD -- France, Portugal, Italy, Spain, and Switzerland.

    In addition to vitamin K, many other fat-soluble nutrients (lycopenes, carotenoids, etc.) in plant foods simply aren't absorbed unless accompanied by fat, which, ironically, renders those "healthy" fat free salad spritzes downright hazardous to health.

  • Anonymous

    12/28/2007 7:33:00 PM |

    Great blog, enjoyed reading about vitamin K2.  

    With recent findings on the importance of bone strengthening supplements and drugs for heart health, would weight lifting be helpful at bringing about plaque regression?

  • Carl H

    12/28/2007 8:14:00 PM |

    What about Miso?  Another fermented soy product.  Not bad + not natto.

  • Dr. Davis

    12/28/2007 11:06:00 PM |

    Hi, Mac--

    Yes, magnesium is among the three nutrients that I fuss about for bone and arterial health, along with K2 and D3.

    Thanks for the heads up on Dr. Eades blog. I've only recently stumbled across his Blog and found it wonderful, full of unique and refreshingly candid comments.

  • Dr. Davis

    12/28/2007 11:07:00 PM |

    No, not specifically. K2 improves bone health and possibly arterial health. Weight lifting improves bone health. But that's as far as the intersection goes.

  • Dr. Davis

    12/28/2007 11:08:00 PM |

    I love miso and was raised on it. But to my knowledge it is not a significant source of K2.

  • Cindy Moore

    12/29/2007 8:29:00 AM |

    "--Coumadin (warfarin) blocks all forms of vitamin K."

    Do you know if there is any evidence that long term (20 yrs+) warfarin use may increase risk?

  • Anonymous

    12/29/2007 8:58:00 AM |

    My research shows that CoQ10 has a structure very similiar to vitamin K.  Perhaps supplementation with CoQ10 may help provide Vitamin K2.

  • Dr. Davis

    12/29/2007 1:21:00 PM |

    Yes. Unfortunately, now several studies have shown that there is greater heart valve and artery calcification with prolonged Coumadin usage. Although the data are very preliminary, there may be benefit to K1 and K2 supplementation, though your doctor's cooperation is required to do this.

  • Harry35

    12/30/2007 1:38:00 AM |

    Here's a list of fermented and unfermented cheeses that I compiled by googling around. Not sure how to tell which of the fermented cheeses have the most K2, though.

    Fermented:

    Aged goat cheese
    Bleu Cheese
    Brie
    Cambozola
    Camebert
    Cantal
    Cheddar
    Cheshire
    Cultured dry cottage cheese
    Edam
    Emmenthal
    Feta
    Gorgonzola
    Gouda
    Gruyere
    Muenster
    Parmesan
    Port du Salut
    Roquefort
    Romano
    Stilton

    Unfermented

    Farmer cheese
    Mescarpone
    Most cottage cheese
    Mozzarella
    Pot cheese
    Processed cheese
    Provolone
    Provatura
    Quark
    Ricotta
    Scamorza

  • Dr. Davis

    12/30/2007 2:07:00 PM |

    Wow! Thanks, Harry.

    I didn't realize that provolone and ricotta were unfermented.

  • chickadeenorth

    12/30/2007 4:37:00 PM |

    Wow great info and timely article...thnx.
    I eat those fermented cheeses that  and have eggs, I use only olive oil though. I read somewhere that any oil that gets sticky on outside of the jug gets sticky inside the body and since canola is one of those I quit using it, wish I could find that article, ( Eades maybe?)what do you folks think.
    So having some oil on veg and salad is great, I don't use those low fat or spritz things are they seem too processed and full of chemicals.

    Thnx Dr D for the excellent info as always.

    So do you eat those slimy soybeans, are they pretty icky or do you think a person could get used to them. Lots of my Japanese guests ( from Japan not North America) bring some of their own food and I have seen these before. Looks kind of like eatin the foods off Fear Factor....j/k.

  • MAC

    12/30/2007 4:48:00 PM |

    Seem to remember reading somewhere recently that if the cheese has the word "culture" in the ingredient list then it is a fermented product. This could mean yogurt and kefir may have K2. Web sources seem to indicate this but didn't find any I consider reliable.

  • Dr. Davis

    12/30/2007 10:54:00 PM |

    I don't think that there's anything wrong with actually eating natto. It's just that it is quite difficult to stomach. I had it several times as a kid and found it thoroughly unappetizing, despite having tried some really exotic stuff like raw octopus and seaweed. Natto was the one thing I simply could not eat.

    The stick oil thing has me stumped. Our bodies digest foods like oil before they make it into the blood stream. Why its behavior in a bottle would have any bearing on its behavior in the body is beyond me.

  • Cindy Moore

    12/31/2007 12:08:00 AM |

    Mary Enig is an excellent source of information about oils. Her general belief is that processed oils (like corn, cannola and soy) are heat treated during the processing and this heat damages the fat molecules, so these fats are essentially spoiled when they are bottled. These oils are also polyunsaturates, which are the least stable of oils, so they should be stored properly and protected from heat, light, etc. (Flax and fish oils are "good" polys, but care should be used to keep these fresh and prevent oxidation)

    I only use virgin olive oil, virgin cocount oil and butter, and I rarely (if ever) use olive for cooking. (I want to try the nut oils, but haven't given them a shot yet).

  • chickadeenorth

    12/31/2007 8:20:00 AM |

    Cindy why don't you use olive oil to cook in at low heat,curious, I thought that was ok if it didnt get too hot. I just got some walnut and almond oil and have to try them.I also use coconut oil to cook in and grapeseed for salads.

    I cannot get vit k 2 in Ca and have a friend going to Florida in 2 days who will buy me some, what is a good name brand and dose,  also a good name brand and dose for DHEA thanks for feedback.

  • Cindy Moore

    12/31/2007 5:51:00 PM |

    chickadeenorth, I don't often us olive in cooking because I've read (Enig I believe) that if it smokes it shouldn't be eaten....and I've had too many instances of the heat getting ahead of me and the oil ending up burned. I just find it easier to use coconut....and then I add butter and/or olive oil at the end to give it flavor, if needed. Mostly I just use the coconut oil.

    I use Source Naturals K, but am also interested in hearing some recommendations. I bought this because I'm told Source Naturals is a good company.

  • Dr. Davis

    12/31/2007 6:10:00 PM |

    We've used Source Naturals, Life Extension, and Jarrow. All seem like the real thing.

  • chickadeenorth

    12/31/2007 8:40:00 PM |

    ..thnx...is this in dry tablet form, what dose of tablet should I get her to pick up, what about DHEA?? name brand and dose.

    Ya I cook with natural gas so keep flame very low and don't over heat anything,I don't use allot as have good pots, maybe should use coconut more often, its adds a nice flavor especially to chicken and pork.

    I think some guests from Japan bought some of those soybeans once in a can, is that how they come, they ate something that looked familiar to your picture.

  • g

    1/1/2008 6:35:00 AM |

    Apparently the ADA have new guidelines coming soon!  AND guess what they advise now!  LOW CARB diets!!

    This is funny...
    http://thefitnessinsider.menshealth.com/2007/12/apparently-hell.html

  • chickadeenorth

    1/1/2008 5:13:00 PM |

    Hmm wonder what pushed their buttons, the powers at be in USA are also supposedly going to recommend a higher dose of Vit D too.
    http://articles.mercola.com/sites/articles/archive/2008/1/1/experts-starting-to-agree-more-vitamin-d-is-better.aspx

  • brassman

    1/1/2008 6:04:00 PM |

    Vitamin K is fat soluble. Will a tablet be absorbed well or do I need a soft gel as with vitamin d?

  • chickadeenorth

    1/1/2008 9:06:00 PM |

    Is this the right DHEA I am looking for, if so I found a source in Canada but still no Vit k 2.Sorry I can't log onto the forum.Smile

    http://www.nutrichem.com/Phosphatidyl-Serine-Complex-23.html

  • Dr. Davis

    1/2/2008 12:10:00 PM |

    The label and info says phosphatidylserine, not DHEA.

  • Dr. Davis

    1/2/2008 12:11:00 PM |

    The data would suggest that, unlike vitamin D, even tablets of K2 are well absorbed.

  • Anonymous

    1/31/2008 1:02:00 AM |

    Hello Dr. Davis,
    Thank you for this great post. We've recently learned that K2 was probably what Weston Price had  called Activator-X, since he had not been in contact with other researchers who were learning about vitamin K at the time.

    Anyway, I can help with the "sticky oil" comment. Oils that oxidize easily become sticky (basically like varnish drying) when exposed to oxygen. This means that canola oil and other less-saturated fatty acids can oxidize (producing free radicals) in the bottle (and MAYBE in the blood - there is oxygen in the blood, but I'm not an expert in blood chemistry). We don't know how long the oil was exposed to air before it was bottled. X-virgin olive oil, on the other hand, has a lot of anti-oxidants built in (and numerous phyto-nutrients), so probably has a longer shelf life. Most Canola oil is a highly processed modern hybrid. The Mediterranean people never lived on Canola oil. The fact that both are monounsaturated is largely irrelevant.  -David

  • Dr. Davis

    1/31/2008 1:33:00 PM |

    Thanks for the help, David.

  • donny

    7/1/2008 6:23:00 PM |

    I hate to comment on an article this old, but I've been reading a lot of stuff online about vitamin k lately. I found this article recently. Really, it looks like an attempt to denigrate food sources of vitamin k in comparison to supplementation.
    First they compared spinach consumption to a vitamin k supplement called konakion, and showed that konakion raised serum levels of k1 maybe seven to eight times as much as 227 grams of boiled spinach with butter. Then, they did a bait and switch, comparing the spinach and butter to a milligram of k2 mixed with 5 grams of butter, and they have a chart with that showing that the k2 with butter raised serum levels of k2 twice as much as the spinach with twenty five grams of butter.
    I'm just wondering if green vegetables, with butter, might be a good way to raise k2 levels after all?

    http://journals.cambridge.org/download.php?file=%2FBJN%2FBJN76_02%2FS0007114596001304a.pdf&code=2e2d0ca6a4129581d36eebf438633b36

  • Anonymous

    12/2/2008 3:05:00 PM |

    "Why would humans have developed a need for a nutrient that is created through fermentation with only small quantities in meats and other non-fermented foods?"

    Perhaps this is an example of how our "sterile" environment is killing us.  Before refrigeration, I am sure humans were subject to much more fermented food.

  • Dane Miller

    4/20/2009 5:58:00 PM |

    I , too hate commenting on an article so old.  Great stuff but canola as a healthy oil?  I think not.  Canola is terrible for you.  Or should I said rapeseed oil.

  • jpatti

    5/25/2009 1:05:39 AM |

    I understand there's a good bit of K2 in unpasteurized milk.  Apparently, grass-fed animals do produce a lot of A, D and K2, but much is destroyed through pasteurization.

    I've recently added raw milk to my diet.  Decided it was worth taking extra insulin for the health benefits.  Can't get raw butter or cream in my state, but am getting it from the same dairy, so it's grass-fed if not raw.

    My bp has dropped about 30/30 without the Lisinopril I was on before.  As hubby says, if it's placebo, it's one worth sticking to.  ;)

    Besides raw milk, I've also about tripled my intake of butter and eggs.  

    And btw, fermenting raw milk yourself is wicked easy.  Take a quart of milk, heat it to around 100-110 degrees (I do this with a quart jar in my crockpot in an inch of water with the lid off).  Remove about a half cup of warmed milk and stir in about 1/4 cup yogurt.  Pour this back into the main container, turn off the crockpot (so it doesn't overheat and kill the culture), and cover with a blanket or such to insulate it.  

    I do this while fixing dinner, in the morning I have yogurt - fermented raw milk, yummy stuff, chockful of K2.  It's not thick like store-bought, more like a drink.  I add blueberries to it most often.

    The point is, with a source of raw milk it takes about 5-10 minutes of "work" to make your own fermented dairy.  You need a quart sized jar, a source of heat, a thermometer, some insulation and some culture (store-bought plain yogurt works fine) - fermented dairy just happens overnight.

  • robbyn

    9/27/2009 9:44:19 AM |

    I know that sauerkraut contains vit k2, but do not know how much per 100g. Has anyone been able to find the figures?

  • Anonymous

    1/5/2010 5:13:32 PM |

    Dear Dr. Davis
    Hello
    Is there a special food diet for patients with aortic valve calcification. How many milligrams
    of vitamin CaLaughing:K2:K:Mg, are recommended for patients.
    Thanks
    Lev

  • Sharon

    2/17/2010 6:56:22 AM |

    Serious question Dr.Davis:    Fibrinogen can create calcification, K2 reduces calcification, natto reduces fibrinogen but is there any clottin risk and conflict in using both agents for a patient with the two dysfunctions?

    Thank you Sharon

  • Anonymous

    3/15/2010 8:46:14 PM |

    Recently had a CT.  After the CT, got up off table and had no pain for 2 weeks.  In constant pain due to significant cervical and lumbar radiculopathy, fibromyalgia, osteoarthritis, etc.  Has anyone ever had a CT with contrast who was in pain and pain gone after the contrast CT?  My doctor told me to blog to see if could find others who drank a liquid and had an IV during the CT.  Was wonderful to have no pain for 2 weeks, and interesting it happened immediately upon rising from the table where the CT was performed.  Anyone exeriencing this, please blog

  • ea

    3/25/2010 1:35:56 AM |

    In http://www.westonaprice.org/On-the-Trail-of-the-Elusive-X-Factor-A-Sixty-Two-Year-Old-Mystery-Finally-Solved.html it says:
    Since the amount of vitamin K1 in typical diets is ten times greater than that of vitamin K2, researchers have tended to dismiss the contribution of K2 to nutritional status as insignificant. Yet over the last few years, a growing body of research is demonstrating that these two substances are not simply different forms of the same vitamin, but are better seen as two different vitamins: whereas K1 is preferentially used by the liver to activate blood clotting proteins, K2 is preferentially used by the other tissues to place calcium where it belongs, in the bones and teeth, and keep it out of where it does not belong, in the soft tissues.
    In other words, to properly use the Calcium in your diet, you need vitamin K2 (as well as A & D) ~ and, since K2 is fat soluble, also fat so that you can absorb the K2.  With K2 the Calcium will be used to strengthen bones and teeth. Without K2 the Calcium will be deposited in joints leading to osteoarthritis, in blood vessels leading to heart attacks and strokes, in eyes leading to cataracts, and in other soft tissues.

    In http://www.westonaprice.org/On-the-Trail-of-the-Elusive-X-Factor-A-Sixty-Two-Year-Old-Mystery-Finally-Solved.html there is also a table of K2 content of various foods.

  • bed frame

    7/6/2010 7:09:17 AM |

    Before I don't know what is vitamin K2 is. But after reading and analyzing your post. Now I know that it is important. I thank you for sharing this very helpful post.

  • Yogi Sinzapatos

    7/29/2010 3:50:33 PM |

    Mixing jpatti's home made raw milk yogurt with flaxseed oil = Dr. Johanna Budwig's cure for cancer (and many other diseases).

  • dermatology laser

    9/30/2010 3:23:32 AM |

    Vitamin K2 might be, for instance more relevant in the form of a supplement or in low-fat dairy.

  • Chuck

    10/21/2010 3:38:37 AM |

    As far as Warfarin blocking the absorption of vitamin K, I am not a big fan of people taking rat poison. Warfarin is the active ingredient in rat poison.

    It is worse than the urine of a pregnant horse. Premarin-- pregnant mare urine. I am American and natto does not taste that bad. Of course it is better to add it to something else. For example no one eats sugar by itself.

    Now raw garlic by itself is painful to eat. But I add it to other foods and it is OK. Raw ginger by itself is also painful to eat.

  • buy jeans

    11/3/2010 4:53:24 PM |

    MK-7 and MK-8,9,10 come from bacterial fermentation, whether in natto, cheese, or in your intestinal tract; MK-4 is naturally synthesized by animals from vitamin K1. While natto is the richest source of the MK-7 form, egg yolks and fermented cheeses are the richest sources of the MK-4 form.

  • Heidi

    11/11/2010 5:34:36 PM |

    Earlier in the thread there was mention made on canola oil. Here's a link that explains the dangers:
    http://www.westonaprice.org/know-your-fats/559-the-great-con-ola.html

  • Jack C

    11/18/2010 3:03:20 AM |

    Somewhere in my files there is a study, from Japan I believe, that found that serum concentrations of MK4 increased after consumption of natto, which contains no MK4. It therefore appears that MK7, 8 and 9 will convert, to some degree, to MK4. Conclusion (mine): Aged cheese can provide all of the vitamin K2 needed. Aged raw milk cheese has most of the benefits of raw milk but is as pathogen free as pasteurized milk due to destruction of pathogens by low pH during aging.  

    While I can not quickly lay my hands on that study, I have found a couple of other related studies of interest.

    Vitamin K is required for activation of osteocalcin. Vitamin K deficiency is associated with low bone mineral density due to increased levels of uncarboxylated (unactivated) osteocalcin(ucOC). The plasma vitamin K2 concentrations required to minimize ucOC increases with age (PMID 16469998). Conclusion: (mine) Eat more aged raw milk cheese as you age to protect you bones.

    Rats readily convert vitamin K1 to K2 but humans do not.

    "Vascular calcification may be species specific to humans. As laboratory animals, such as the rat, grow old, they suffer from only mild arterial calcification" (PMID 18772323): Conclusion (mine): K2 is the answer: Eat more raw milk aged cheese as you get older to prevent calcification of arteries.

    Jack C.

  • Gillian

    1/17/2011 5:13:44 PM |

    Hi, Dr Davis
    I´ve read in some earlier comment of yours, that natto is not really a reliable source for K2, is that so and if, then why?
    I also wonder why I sometimes feel pain in my legs when eating cream.
    I have seen the famous photographer from Sweden that have filmed arteries and showed that cream supposedly block the arteries..
    What is your opinion??

  • Lobster bake

    2/18/2011 9:17:08 AM |

    Thanks, very well written post, found it through a random Google search and I shared it on my Facebook. This Vitamin K foods are very helpful to keep our body healthy and young.

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Chocolate almond biscotti

Chocolate almond biscotti

Biscotti are twice-baked biscuits or cookies that are perfect for dipping into coffee, latté, or espresso. These wheat-free, low-carb biscotti are rich with the taste of chocolate and almonds.

Yield: approximately 15 biscotti



Ingredients:

2 cups almond meal
½ cup chopped walnuts
1/4 cup cocoa powder (undutched)
½ cup dark chocolate chips
Sweetener equivalent to ½ cup sugar (e.g., liquid stevia, Truvia)
½ cup ricotta cheese, room temperature (replace with coconut milk if lactose intolerant)
4 tablespoons butter, melted (replace with coconut oil if lactose intolerant)
2 large eggs
¼ cup milk, unsweetened almond milk, or soy milk
¼ cup almond, peanut, or sunflower seed butter, room temperature

Preheat oven to 350º F.

Mix almond meal, walnuts, sweetener, cocoa powder, and chocolate chips in bowl. Mix in ricotta, butter, eggs, milk, and nut butter and blend by hand thoroughly.

Pour mix onto baking pan lined with parchment paper or greased with coconut oil or other oil. Shape into loaf approximately 1 inch deep and 3½ to 4 inches in width. Place in oven and bake for 40 minutes.

Remove loaf and allow to cool 15 minutes. Slice into approximately ¾-inch widths and lay each biscotto on its side on baking pan. Put back in oven for 10 minutes.

Remove pan and flip biscotti over. Place back in oven and bake an additional 5 minutes. Remove and cool.

Optional: For a little dark chocolate "icing":
Melt 3-4 oz semisweet or dark chocolate in microwave (in 15 second increments until melted) or in metal bowl placed in heated water. Stir in 1-2 teaspoons butter.
Dip each biscotti into melted chocolate mix or drizzle chocolate mixture over top of each biscotto.

Comments (8) -

  • sally

    7/22/2011 3:26:24 AM |

    SOY milk! Surely you know all the ills of soy, probably worse than wheat Smile

    Kaayla Daniels book THE WHOLE SOY STORY is a MUST read!

    They look yummy, thanks

  • Kurt

    7/22/2011 12:16:07 PM |

    You wrote that butter "contains the highest exogenous AGE content of any known food." Should we be eating it?

  • Kim B

    7/22/2011 5:09:57 PM |

    Sally,
    You're right, soy (especially soy available in USA) should never be an option, and although it is listed in the recipe, I do not see that as an endorsement by Dr Davis.

    Just use the almond milk. It tastes loads better anyway, and the recipe is wonderful   ;)

  • Teresa

    7/22/2011 9:02:47 PM |

    Do you have any substitutions to suggest for those who are allergic to nuts?  Perhaps ground flax seed in place of the almond meal, and skip the walnut?

  • Dr. William Davis

    7/24/2011 3:34:15 PM |

    Hi, Kurt--

    I think that modest exposure is harmless. It's the "drown everything in butter" that I see some people practicing that I believe may be harmful.

  • Dr. William Davis

    7/24/2011 3:35:23 PM |

    Hi, Teresa--

    Yes, ground flaxseed is an excellent replacement for nut meals. However, it changes the texture and need for moisture, as well as the balance of other ingredients. It may take an experiment or two to get it just right. Please let me know how your "experiments" go!

  • reizen

    7/26/2011 12:41:40 PM |

    Hi,

    I used to get emails whenever there was a blog post but that stopped in May.  I tried to resubscribe but am told that my email is already in the system.  Any thoughts?

  • Fantola Search Engine

    8/27/2011 4:35:19 AM |

    Humm thats nice! thanks for the recipe. it looks delicious.

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Amber’s Top 35 Health and Fitness Tips

Amber’s Top 35 Health and Fitness Tips

This year I joined the 35 club!  And in honor of being fabulous and 35, I want to share 35 health and fitness tips with you! 

1.  Foam rolling is for everyone and should be done daily. 
2.  Cold showers are the best way to wake up and burn more body fat. 
3.  Stop locking your knees.  This will lead to lower back pain. 
4.  Avoid eating gluten at all costs. 
5.  Breath deep so that you can feel the sides or your lower back expand. 
6.  Swing a kettlebell for a stronger and great looking backside. 
7.  Fat is where it’s at!  Enjoy butter, ghee, coconut oil, palm oil, duck fat and many other fabulous saturated fats. 
8.  Don’t let your grip strength fade with age.  Farmer carries, kettlebells and hanging from a bar will help with that. 
9.  Runners, keep your long runs slow and easy and keep your interval runs hard.  Don’t fall in the chronic cardio range. 
10.  Drink high quality spring or reverse osmosis water. 
11.  Use high quality sea salt season food and as a mineral supplement. 
12.  Work your squat so that your butt can get down to the ground.  Can you sit in this position? How long?
13.  Lift heavy weights!  We were made for manual work,.   Simulate heavy labor in the weight room. 
14.  Meditate daily.  If you don’t go within, you will go with out.  We need quiet restorative time to balance the stress in our life. 
15.  Stand up and move for 10 minutes for every hour your sit at your computer. 
16. Eat a variety of whole, real foods. 
17.  Sleep 7 to 9 hours every night. 
18.  Pull ups are my favorite exercise.  Get a home pull up bar to practice. 
19.  Get out and spend a few minutes in nature.  Appreciate the world around you while taking in fresh air and natural beauty. 
20.  We all need to pull more in our workouts.  Add more pulling movements horizontally and vertically. 
21. Surround yourself with health minded people. 
22. Keep your room dark for deep sound sleep.  A sleep mask is great for that! 
23. Use chemical free cosmetics.  Your skin is the largest organ of your body and all chemicals will absorb into your blood stream. 
24. Unilateral movements will help improve symmetrical strength. 
25. Become more playful.  We take life too seriously, becoming stress and overwhelmed.  How can you play, smile and laugh more often?
26.  Choose foods that have one ingredient.  Keep your diet simple and clean. 
27.  Keep your joints mobile as you age.  Do exercises that take joints through a full range of motion. 
28. Go to sleep no later than 10:30pm.  This allows your body and brain to repair through the night. 
29. Take care of your health and needs before others.  This allows you to be the best spouse, parent, coworker, and person on the planet. 
30.  Always start your daily with a high fat, high protein meal.  This will encourage less sugar cravings later in the day. 
31. Approach the day with positive thinking!  Stinkin’ thinkin’ only leads to more stress and frustration. 
32. You are never “too old” to do something.  Stay young at heart and keep fitness a priority as the years go by. 
33. Dream big and go for it. 
34.  Lift weights 2 to 4 times every week.  Strong is the new sexy. 
35.  Love.  Love yourself unconditionally.  Love your life and live it to the fullest.  Love others compassionately. 

Amber B.
Cureality Exercise and Fitness Coach
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DIRECT Study result: Low-carb, Mediterranean diets win weight-loss battle

DIRECT Study result: Low-carb, Mediterranean diets win weight-loss battle

Drs. Iris Shai and colleagues released results of a new Israeli study, the Dietary Intervention Randomized Controlled Trial (DIRECT) Trial, that compared three different diet strategies. Of those tested, a low-carbohydrate diet was most successful at achieving weight loss.

You can find the full-text of the study on the New England Journal of Medicine website.

322 participants followed one of three diets over two year period. Compared head-to-head, the (mean) weight loss in each group was:

• 2.9 kg (6.4 lbs) for the low-fat group
• 4.4 kg (9.7 lbs) for the Mediterranean-diet group
• 4.7 kg (10.3 lbs) for the low-carbohydrate group

(Average age 52 years at start; average body-mass index, or BMI, 31.)

The conclusion was that the low-carb diet performed the best, with 60% greater weight loss, with the Mediterranean diet a close second.


The diets

The low-fat diet was based on the American Heart Association diet, with 30% of calories from fat (10% from saturated fat) and food choices weighted towards low-fat grains, vegetables, fruits, and legumes and limited additional fats, sweets, and high-fat snacks; calorie intake of 1500 kcal per day for women and 1800 kcal per day for men was encouraged.

The Mediterranean diet was a moderate-fat diet rich in vegetables, with reduced red meat, and poultry and fish replacing beef and lamb. Total calories from fat of 35% per day or less was the goal, with most fat calories from olive oil and a handful of nuts. Like the low-fat program, calories were limited to 1500 kcal per day for women, 1800 kcal per day for men.

The low-carbohydrate diet was patterned after the popular Atkins’ program, with 8% participants achieving the ketosis that Dr. Atkins’ advocated as evidence that a fat-burning metabolism was activated, rather than sugar-burning as fuel. For the 2-month “induction phase,” 20 grams of carbohydrates per day was set as the goal, followed by 120 grams per day once the weight goal was achieved. Unlike the other two diets, calories, protein and fat were unlimited.


Weight loss, lipids, inflammation

You can see from the weight loss graph that the low-carb approach exerted the most dramatic initial weight loss. Interestingly, much of the weight-loss benefit was lost as the carbohydrate intake increased, by study design, back to 120 mg per day. However, the other two diet approaches showed similar phenomena of “giving back” some of the initial weight loss.

The low-carbohydrate diet exerted the greatest change in cholesterol, or lipid, panels: increased HDL 8.4 mg/dl vs. 6.3 mg/dl on low-fat; the triglyceride response was the most dramatic, with a reduction of 23.7 mg/dl vs. 3.7 mg/dl on low-fat. Interestingly, the LDL cholesterol-reducing effect of all three diets was modest, with the most reduction achieved by the Mediteranean diet.

The inflammatory measure, C-reactive protein (CRP), was reduced most effectively by the low-carb and Mediterranean diets, least by the low-fat diet. HbA1c, a measure of long-term blood sugar, dropped significantly more on the low-carb diet.

When the final dietary composition was examined, interestingly, there really were only modest differences among the three diets, with 8% less calories from carbs, 8% greater calories from fat, comparing low-carb to low-fat, with Mediterranean intermediate.



Taken at face value, this useful exercise quite clearly shows that, from the perspective of weight loss and correction of metabolic parameters like triglycerides, HDL,CRP, and blood sugar, low-carbohydrate wins hands down, with Mediterranean diet a close second.

It also suggests that a return to a carbohydrate intake of 120 mg/day allows a partial return of initial weight lost, as well as deterioration of metabolic parameters after the initial positive changes.

Although the study has already received some criticism for such potential flaws as the modest number of Atkins’ followers achieving ketosis (8%), suggesting lax adherence, and the reintroduction of the 120 mg/day carbohydrate advice, I can suspect that these may have been compromises drawn to satisfy some Institutional Review Board. (Whenever a study is going to be conducted involving human subjects, a study needs to pass through the review of an Institutional Review Board, or IRB. IRB’s, while charged to protect human subjects from experimental abuses, also tend to be painfully conservative and will block a study or demand changes even if they are not dangerous, but just veer too far off the mainstream.)


However, several unanswered questions remain:

1) How would the diets have compared if the carbohydrate restriction were continued for a longer period, or even indefinitely? (The divergences would likely have been dramatic.)
2) Will low-carb exert the same cardiovascular event reduction that the Mediterranean approach has shown in the Lyon study and others?
3) Are there effects on health outside of the measures followed that differ among the three diets, such as cancer? (I doubt it, especially given the modest real differences over time. But this will be the objection raised by various "official" organizations.)


I would further propose that:

Low-fat diets are dead

The AHA will cling to their version of low-fat diet, based on difficulty in changing course for any large, consensus-driven organization, not to mention the substantial ($100’s of millions) revenues derived from endorsing low-fat manufactured products. The AHA will also point to the lack of difference in LDL cholesterol among the three, since they cannot get beyond the fact that there’s more to coronary risk—a lot more—than LDL.


Off-the-shelf diets achieve off-the-shelf results

If you just need a T-shirt, a medium might fit fine. But if you’d like a nicely fitting suit or dress, then tailoring to your individual proportions is needed. When aiming towards maximizing benefits on lipoproteins and coronary risk, none of these diets achieve the kinds of changes we often need for coronary plaque reversal, as in the Track Your Plaque program. That requires making dietary changes that exert maximal effects on lipoprotein patterns.

Comments (14) -

  • Jenny

    7/19/2008 3:30:00 PM |

    Dr. Eades also has an interesting take on this study on his blog.  
    http://www.proteinpower.com/drmike/weight-loss/low-carb-diet-trumps-low-fat-diet-yet-again/#more-1286
    Many comments responding to it are interesting and worth reading as well, (Dr. Eades appears to have many readers with the same ability to cut through BS as those of the HeartScanBlog )  but two that I found especially revealing deal with how this study was reported by the press outside the US.  According to one commenter, in the UK the Daily Telegraph headline said, "Low-fat diets 'not as effective for weight loss'", and the Daily Mail's, "the controversial Atkins Diet is 'safe and far more effective than a low-fat one',study shows".   Another commenter said that in the Philippines, the Philippine Inquirer said "Low-carb diet proven best for weight control." In this country even the way an "objective" report on this subject is titled in the press seems colored by  distaste (fear?) and reluctance to give the facts their due.

  • Juhana Harju

    7/19/2008 4:52:00 PM |

    You have an interesting blog that I have been following for some time already. Personally I am a proponent of Mediterranean diet, but I would like to say that I do not agree with your claim that low fat diets are dead.

    It should be noticed that the DIRECT study was a weight loss diet for people who were obese (average BMI 31). It is well known that low fat diets are not ideal for people who are overweight or people with insulin resistance. However, low fat diets can be quite suitable for lean and active people. Japan is a good example of a population where the diet is still low fat and its coronary heart disease risk is low.

  • Aaron

    7/20/2008 7:22:00 PM |

    This study didn't prove much.  Look at the weight gain that occurred after 1 year on the diet (2 year study).  When is there going to be a true study done on a nutrient dense low fat diet (not 30% of calories like was done in this study) vs a paleo type diet and a not a vegetarian atkins-esc diet.  This study just adds to confusion.

  • Anonymous

    7/20/2008 10:11:00 PM |

    Japan may have lower heart attacks but they are suffering from thyroid problems from so called health food "soy".

  • Juhana Harju

    7/21/2008 5:04:00 AM |

    Anonymous wrote:

    "Japan may have lower heart attacks but they are suffering from thyroid problems from so called health food 'soy'."

    Soy has some harmful effects but I think that the benefial effects of soy outweigh them. Japan has one of the highest life-expectancies and the highest healthy life-expectancy in the world. For me this shows that much of what they are doing is probably right inspite of their stressful working life.

    PS. The blog takes very long to download, probably due to the Digg application and many other features.

  • Jeff Consiglio

    7/22/2008 12:55:00 PM |

    I found it interesting that certain biomarkers became less favorable within the low carb group, when they upped carbs to a mere 120 grams per day. That sure is motivation to watch one's intake of carbs! BTW, I love your take on the AHA. Cocoa Puffs are "heart friendly" just because they are low in fat? Pleeeease!

  • George

    7/22/2008 8:49:00 PM |

    I wonder if Dr. Davis could comment or rebut Dr. Ornish's expected rebuttal to this study in the latest newsweek issue. Here is the link http://www.newsweek.com/id/146641

    Great blog, great information

  • Stephen

    7/22/2008 11:58:00 PM |

    Gee, if they are making that much from endorsements, disclaimers are appropriate every time they push a diet that connects to an endorsement.

    http://www.proteinpower.com/drmike/wp-content/uploads/2008/07/taubes-response-to-bray-ob-reviews.pdf

    was great too.

    However, most people who are concerned with diet are those who are overweight.

    Juhana, yes, when I had time to exercise 20+ hours a week, an entirely different pattern of eating was appropriate than when I had a job and many fewer hours.

    I don't see the point.  Few of us are currently competitive athletes right now.

  • Juhana Harju

    7/23/2008 5:33:00 AM |

    Stephen, Japanese are doing fine without 20 hours of exercise a week.

    In my opinion, reducing carbs is necessary only when you already have an abnormal glucose metabolism due to overeating, high intake of refined carbs and sedentary lifestyle. High prevalance of overweight, obese and diabetic people is clearly a modern phenomenon.

  • renegadediabetic

    7/23/2008 2:11:00 PM |

    I too am not sure that low fat is dead.  I still hear a lot of low fat nonsense everywhere I turn.

    Low fat should be dead, but there are too many folks in the medical-dietary establishement who want to keep it on life support.

  • Anonymous

    2/2/2010 12:52:35 AM |

    My friend and I were recently talking about the prevalence of technology in our day to day lives. Reading this post makes me think back to that discussion we had, and just how inseparable from electronics we have all become.


    I don't mean this in a bad way, of course! Ethical concerns aside... I just hope that as the price of memory falls, the possibility of transferring our brains onto a digital medium becomes a true reality. It's one of the things I really wish I could experience in my lifetime.


    (Posted on Nintendo DS running [url=http://kwstar88.livejournal.com/491.html]R4 SDHC[/url] DS FPost)

  • Generic Viagra

    9/21/2010 1:47:11 PM |

    Low-carb diets help to lose weight in a matter of time but these help to keep the body healthy and strong. buy viagra viagra

  • buy jeans

    11/3/2010 6:45:35 PM |

    The Mediterranean diet was a moderate-fat diet rich in vegetables, with reduced red meat, and poultry and fish replacing beef and lamb. Total calories from fat of 35% per day or less was the goal, with most fat calories from olive oil and a handful of nuts. Like the low-fat program, calories were limited to 1500 kcal per day for women, 1800 kcal per day for men.

  • farseas

    7/11/2011 8:32:53 PM |

    Could you please quote sources that show that the Japanese have a thyroid problem induced by soy.  I think that soy bashing is a bunch of hype.

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Coenzyme Q10 and statin drugs

Coenzyme Q10 and statin drugs

Although drug manufacturers claim that muscle side effects from statin drugs occurs in only around 2% or people or less, my experience is very different.

I see muscle weakness and achiness develop in the majority of people taking Lipitor, Crestor, Zocor, Vytorin, etc. I'd estimate that nearly 90% of people get these feelings sooner or later.

Thankfully, the majority of the time these feelings are annoyances and do not lead to any impairment. Full-blown muscle destruction is truly rare--I've seen it once in over 10 years and thousands of patients.

The higher the dose of statin drug and the longer you take it, the more likely you're going to have muscle aches.

I experienced a strange phemomenon myself today. I worked outdoors for about 4 hours, pulling weeds, digging in the dirt, spreading topsoil. (I have an area of overgrowth in the front yard.) Admittedly, I worked pretty hard and it was a warm, humid day.

I was sore, as you'd expect at age 49. But, much more than that, I was exhausted--my muscles ached and I had barely enough strength to get up the stairs.

Hoping for some relief, I took an extra dose of coenzyme Q10. I usually take 50-100 mg per day. Today, when I felt this overwhelming muscle fatigue, I took an additional 200 mg. Within 10 minutes, I felt a surge of energy. It was, in fact, a perceptible, quite dramatic feeling.

I am thoroughly convinced, through my own experiences on Lipitor (I have a high LDL particle number despite a healthy lifestyle, among other abnormalities), and the experiences of many other people, that coenzyme Q10 can be an extremely useful tool to minimize the muscle aches and weakness of the statin drugs.

If you do indeed need to take one of these agents, coenzyme Q10 is worth knowing about. Supplementing coenzyme Q10 has, for me, been a real lifesaver. For many people, LDL reduction is a crucial part of their heart scan score control program. In my experience, many of them would not be able to take the drug without eozyme Q10.
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