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I wonder why my vitamin D 25 hydroxy is so much lower


Member Forum >> Vitamin D >> I wonder why my vitamin D 25 hydroxy is so much lower

Join Date: 11/17/2017
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Posted: 12/24/2019 6:29:20 AM
Edited: 12/24/2019 6:37:59 AM (3)

I’ve been taking 5000 IU of D3 in gel caps with olive oil for like 4 years now.

Back in Dec of 2017 I was at 54.6.  But this year in Nov 2019 I was only at 38.3.

Any ideas as to why it could be lower?   I’ve since doubled my D3 to 10K IU per day.



I do have the homozygous mutation for VDR Taq in Genetic Genie Methylation Profile (using 23AndMe raw data).  I guess this might have something to do with why I have problems with Vit D?  My brother was at 11 ng/mL the other day!  He’s on 15K IU per day now.  I am guessing he might have this same mutation.. need to order the 23AndMe test for him too.  He’s been suffering severe depression the past 6 months and started on anti-depressent.. I am sure it was probably just due to the Vit D deficiency.  I read that Vit D is needed to make the enzymes to create dopamine.. we are probably both low on dopamine from this VDR Taq mutation.
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Thats impressive you know how many hours you are outside :)    Thanks for sharing all that! :) 
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Posted: 12/25/2019 7:34:46 AM
Edited: 12/25/2019 7:37:38 AM (1)


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Boo, oh thanks for that.. that could explain things.  I had lost a lot of weight when it was 54 vs. the 38 it is now, taking the same dose of 5000 IU every day.
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In my case the fluctuations in serum levels happened without fluctuations in weight. With a constant BMI of 20.
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